Search for dissertations about: "Endokrinkirurgi"

Showing result 1 - 5 of 13 swedish dissertations containing the word Endokrinkirurgi.

  2. 1. Hypoparathyroidism after thyroid surgery- rates, risks, prevention and consequences

    Author : Matilda Annebäck; Olov Norlén; Peter Stålberg; Jakob Hedberg; Erik Nordenström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thyroidectomy; hypoparathyroidism; hypocalcemia; parathyroid hormone; vitamin D; health-related quality of life; Kirurgi; Surgery;

    Abstract : Hypoparathyroidism is the most common complication after thyroid surgery and associated with short- and long-term consequences. The lack of a consensus on the definition of hypoparathyroidism has led to a broad range in the rates reported in the literature. READ MORE

  4. 2. Calcium Homeostasis in Patients with Graves' Disease

    Author : Maria Annerbo; Per Hellman; Peter Stålberg; Peyman Björklund; Filipsson Nyström Helena; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Graves Disease; Calcium homeostasis; Total thyroidectomy; Bone metabolism; Calcium sensing receptor; Surgery; Kirurgi;

    Abstract : Patients with Graves´ Disease (GD) have a higher risk of developing more severe and prolonged hypocalcaemia after total thyroidectomy (TT) than patients who undergo surgery for benign atoxic goitre. Since TT is the most effective treatment for GD, it is crucial to identify mechanisms for postoperative hypocalcaemia. READ MORE

  5. 3. Studies of epigenetic deregulation in parathyroid tumors and small intestinal neuroendocrine tumors

    Author : Elham Barazeghi; Gunnar Westin; Peter Stålberg; Per Hellman; Christofer Juhlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epigenetics; 5hmC; TET1; TET2; parathyroid tumors; SI-NET; RRBS; PTPRM;

    Abstract : Deregulation of the epigenome is associated with the initiation and progression of various types of human cancers. Here we investigated the level of 5-hydroxymethylcytosine (5hmC), expression and function of TET1 and TET2, and DNA methylation in parathyroid tumors and small intestinal neuroendocrine tumors (SI-NETs). READ MORE

  6. 4. Small Intestinal Neuroendocrine Tumors : Clinical Studies, Novel Serum Biomarkers and Sensitivity to Cytotoxic and Targeted Agents

    Author : Kosmas Daskalakis; Peter Stålberg; Per Hellman; Olov Norlén; Robert Bränström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SI-NET; fibrosis; locoregional surgery; liver transplantation; biomarkers; ex vivo sensitivity.;

    Abstract : Small Intestinal Neuroendocrine Tumors (SI-NETs) are indolent neoplasms with an increasing annual incidence of approximately 1/100 000 people. They are often diagnosed at a late stage, restricting treatment efficacy. READ MORE

  7. 5. Genetic Aspects of Endocrine Tumorigenesis : A Hunt for the Endocrine Neoplasia Gene

    Author : Alberto Delgado Verdugo; Peyman Björklund; gunnar westin; Per Hellman; Filip Farnebo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Exome sequencing; SDHAF2; epigenetics; methylation; methylation array; Sanger sequencing; pheochromocytoma; SI-NETs; carcinoid; oncology; endocrine surgery; parathyroid; Genetics; Genetik; Kirurgi; Surgery;

    Abstract : Endocrine tumors arise from endocrine glands. Most endocrine tumors are benign but malignant variants exist. Several endocrine neoplasms display loss of parts of chromosome 11 or 18, produce hormones and responds poorly to conventional chemotherapeutics. The multiple endocrine neoplasia syndromes are mainly confined to endocrine tumors. READ MORE