Search for dissertations about: "Endostatin"
Showing result 1 - 5 of 13 swedish dissertations containing the word Endostatin.
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1. Effects of sex steroids and tamoxifen on matrix metalloproteinase activity and generation of endostatin in the breast
Abstract : Sex steroids are inevitable in women. However, long-term exposure to sex steroids increases the risk of breast cancer. A complete understanding of sex steroid control of the breast and how it relates to breast cancer risk is still lacking. READ MORE
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2. Regulation of Angiogenesis
Abstract : Angiogenesis is the formation of new blood vessels from pre-existing ones. New blood vessel formation is fundamental in processes such as reproduction, embryonic development and wound healing. Growth of neoplasms is accompanied by increased angiogenesis. This thesis describes cellular and molecular mechanisms of importance for angiogenesis. READ MORE
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3. Endothelial differentiation and angiogenesis regulation
Abstract : Angiogenesis can be defined as the formation of new blood vessels from pre-existing ones. Angiogenesis is required for development and maintenance of our vascular system and thus of fundamental importance to our existence. READ MORE
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4. Decoding Heparan Sulfate
Abstract : Heparan sulfate (HS) is a polysaccharide of glycosaminoglycan type composed of alternating hexuronic acid [either glucuronic acid (GlcA) or iduronic acid (IdoA)] and glucosamine (GlcN) units that can be sulfated in various positions. HS binds to a large number of proteins and these interactions promote many biological processes, including cell adhesion and growth factor signaling. READ MORE
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5. Stromal components and micro-RNAs as biomarkers in pancreatic cancer
Abstract : Background Pancreatic ductal adenocarcinoma (PDAC) patients have the poorest 5-year survival rates of all cancer forms. It is difficult to diagnose at early disease stages, tumour relapse after surgery is common, and current chemotherapies are ineffective. READ MORE