Search for dissertations about: "Endothelial Cells physiology"

Showing result 1 - 5 of 32 swedish dissertations containing the words Endothelial Cells physiology.

  1. 1. Properties of the endothelial cells and the glomerular barrier

    Author : Jenny Sörensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

    Abstract : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. READ MORE

  2. 2. Identification and characterization of new mechanisms in cardiovascular estrogen signaling

    Author : Anders Holm; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; endothelial cells; vascular smooth muscle cells; estrogen; GPR30 GPER1; inflammation; calcium; neovascularization; microtubule;

    Abstract : Women before menopause are protected from cardiovascular disease compared to age-matched men through mechanisms associated with the female sex hormone estrogen. There are three known estrogen receptors named ERα, ERβ and GPR30/GPER1, which are all three receptors are expressed in the cardiovascular system. READ MORE

  3. 3. Hyaluronan receptors of liver endothelial cells, their purification and characterisation

    Author : Peter A. G. McCourt; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; hyaluronan; scavenger receptors; ICAM-1; liver endothelial cells; Biokemi; Biochemistry; Biokemi; fysiologi; Physiology;

    Abstract : Hyaluronan (HA) is a polysaccharide common throughout the connective tissues. and is found at low concentrations in the blood. The major site of its clearance is via an endocytic receptor on liver endothelial cells (LEC). This process is vital, as excessive serum levels of HA lead to clotting disorders and overly viscous blood. READ MORE

  4. 4. Localization of lipoprotein lipase in mouse pancreas, kidney and placenta : impact of metabolic disturbances on cellular distribution and activity regulation

    Author : Rakel Nyrén; Gunilla Olivecrona; Paolo Parini; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; pancreas; kidney; placenta; angiopoietin-like protein 4; high-fat diet; obesity; mice; PET CT; nutritional status; triglyceride; GPIHBP1; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Abstract : Lipoprotein lipase (LPL) is the key enzyme for metabolism of triglycerides in plasma lipoproteins. In recent years many new facts about the enzyme and its regulation have been uncovered. The endothelial membrane protein GPIHBP1 translocates LPL through endothelial cells and holds the enzyme in place at the luminal side of the capillary endothelium. READ MORE

  5. 5. Leukocytes in Angiogenesis : Learning from Transplanted Pancreatic Islets

    Author : Gustaf Christoffersson; Mia Phillipson; Kristian Pietras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; angiogenesis; pancreatic islet transplantation; islets of Langerhans; diabetes mellitus; leukocytes; neutrophils; macrophages; pericytes; MMP-9; VEGF-A; Medical Science; Medicinsk vetenskap;

    Abstract : Angiogenesis, the growth of new blood vessels, is a complex process involving several cell types and molecular signals. Excessive vascular growth is a problem in tumors, and insufficient vascularization hampers the function of transplanted insulin-producing pancreatic islets. READ MORE