Search for dissertations about: "Endothelial barrier permeability"

Showing result 1 - 5 of 28 swedish dissertations containing the words Endothelial barrier permeability.

2. 1. Endothelial-leukocyte interactions

   Author : Maria Olofsson; Diabetes - öpatofysiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Histology; endothelial cell; leukocyte; apoptosis; mitochondria; heparin binding protein; vascular permeability; E-selectin; migration; rolling; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

   Abstract : This thesis describes early inflammatory responses involving interactions between leukocytes and the endothelial lining of the blood vessel wall. An adhesion molecule, E-selectin, which is upregulated on interleukin-1 activated endothelium, was found to mediate rolling between leukocytes and endothelial cells in vivo. READ MORE

4. 2. Endothelial Barrier Dysfunction in Multiple Organ Injury. An Experimental Study in Rats

   Author : Xiaoming Deng; Lund Kirurgi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; orthopaedics; Surgery; Endothelial barrier permeability; Multiple organ dysfunction syndrome; Zymosan; traumatology; Kirurgi; ortopedi; traumatologi;

   Abstract : Multiple organ dysfunction syndrome (MODS) is still the leading cause of mortality in the surgical intensive care unit. The effect on among others endothelial barrier permeability, reticuloendothelial function, organ function and protease-antiprotease activities was studied following a variety of challenges, especially over-activation of macrophages induced by intraperitoneal administration of zymosan. READ MORE

5. 3. Properties of the endothelial cells and the glomerular barrier

   Author : Jenny Sörensson; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

   Abstract : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. READ MORE

6. 4. Dynamics of the glomerular filtration barrier - Physiological and pathophysiological aspects

   Author : Josefin Axelsson; Njurmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerular filtration barrier; Glomerular permeability; Microalbuminuria; Albumin; Ficoll; Sieving Coefficient; Rats;

   Abstract : The dynamic properties of the glomerular filtration barrier (GFB) are of fundamental importance for the understanding of the physiology and pathophysiology of microalbuminuria and proteinuric diseases. In the studies of this doctoral thesis the properties of the rat glomerular filtration barrier were investigated under resting conditions and following a number of challenges using highly sensitive gel filtration chromatography (HPSEC) detection of FITC-Ficoll in serum and urine. READ MORE

7. 5. Mechanisms for leukocyte-mediated adjustment of endothelial barrier function

   Author : Narinder Gautam; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Inflammation; leukocyte extravasation; endothelial cells; vascular permeability; plasma leakage integrin signaling; heparin binding protein; contact phase; bradykinin.;

   Abstract : Extravasation of polymorphonuclear leukocytes (PMN) and associated plasma exsudation are key events in the inflammatory process. The mechanism by which activated PMN may induce increased vascular permeability for macromolecules is not fully understood but crucially dependent on an intact leukocytic beta2 integrin (CD11/CD18) adhesion receptor function. READ MORE