Search for dissertations about: "Endothelium physiology"

Showing result 1 - 5 of 23 swedish dissertations containing the words Endothelium physiology.

  2. 1. Properties of the endothelial cells and the glomerular barrier

    Author : Jenny Sörensson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Capillary permeability; kidney glomerulus physiology; isolated perfused kidney; endothelium; orosomucoid; charge; horseradish peroxidase; inflammation; proteoglycan; cAMP.;

    Abstract : The kidneys are vital organs that filter plasma to produce 180 liters of primary urine per day. Only 1% of this volume is excreted and the rest is reabsorbed. Naturally, such huge amounts of fluid must be well controlled to maintain the homeostasis, which is a prerequisite for life. READ MORE

  4. 2. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease

    Author : Olof Schreiber; Lena Holm; Mia Phillipson; Henrik Sjövall; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammatory bowel diseases; experimental colitis; DSS; TNBS; colonic mucosal blood flow; laser-doppler flowmetry; colonic mucus thickness; MUC2; colonic mucosal barrier function; iNOS; eNOS; probiotics; Lactobacilli; Lactobacillus reuteri; colonic microbiota; T-RFLP; bacterial translocation; intravital microscopy; P-selectin; leukocyte recruitment; platelet recruitment; Physiology; Fysiologi; Physiology; Fysiologi;

    Abstract : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. READ MORE

  5. 3. Ion channels and electrical activity in vascular smooth muscle: Effects of calcium store depletion, cholesterol and cholesterol-lowering drugs

    Author : Andreas Bergdahl; Kärlfysiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; statins; endothelin; cholesterol; caveolae; smooth muscle; TRP; Ca2 channels; SOC;

    Abstract : Smooth muscle cells (SMCs) in the vessel wall contract to regulate blood flow and pressure, a function essential for normal circulation through tissues. On the other hand, migration and proliferation of SMCs are important factors in vascular disease, such as atherosclerosis and restenosis following surgical dilatation. READ MORE

  6. 4. Local regulation of the endogenous fibrinolytic system in man

    Author : Thordis Hrafnkelsdottir; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tissue-type plasminogen activator; plasminogen activator inhibitor type-1; endothelium; extracellular nucleotides; hypertension; chronic renal failure;

    Abstract : The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (tPA). The endothelium synthesises and stores tPA and regulated release of the enzyme is an important mechanism for removal of fibrin from blood vessels. Plasminogen activator inhibitor type-1 (PAI-1) is the main inhibitor of tPA. READ MORE

  7. 5. Aspects on lipoprotein lipase and atherosclerosis

    Author : Lucyna Neuger; Philip Barter; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical physiology; Klinisk fysiologi;

    Abstract : Lipoprotein lipase (LPL) hydrolyses blood lipids at the vascular endothelium. This action makes fatty acids available for tissue metabolic requirements. LPL is anchored to the endothelium by electrostatic forces and may act as a bridge connecting lipoproteins to cell surfaces. READ MORE