Search for dissertations about: "Endotoxin"

Showing result 1 - 5 of 133 swedish dissertations containing the word Endotoxin.

  1. 1. Interleukin-17 in endotoxin-induced airway inflammation

    Author : Olof Prause; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; endotoxin; T lymphocytes; neutrophils; secondary mediators; MMP-9;

    Abstract : .... READ MORE

  2. 2. Antibacterial Effect and Inflammatory Response in Relation to Antibiotic Treatment of Sepsis

    Author : Paul Skorup; Jan Sjölin; Miklós Lipcsey; Kristoffer Strålin; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sepsis; Septic shock; Antibiotics; Aminoglycoside; β-lactam; Bacteria; E. coli; Inflammation; Cytokines; Endotoxin; Porcine; ICU; Secondary sepsis; Endotoxin-tolerance.; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis defines as life-threatening organ dysfunction caused by a dysregulated host response to infection. The importance of early administration of antibiotics in septic shock is undisputed, but the optimal antibiotic choice remains uncertain. READ MORE

  3. 3. Modulating Organ Dysfunction in Experimental Septic Shock : Effects of Aminoglycosides, Antiendotoxin Measures and Endotoxin Tolerance

    Author : Markus Castegren; Jan Sjölin; Claes Frostell; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipopolysaccharide; animal model; pig; tobramycin; endotoxin elimination; immunoparalysis; secondary sepsis; Infectious diseases; Infektionssjukdomar; Infektionssjukdomar; Infectious Diseases;

    Abstract : Sepsis is a common diagnose in the intensive care population, burdened with a high mortality. The systemic inflammatory reaction underlying the development of septic organ dysfunction can be modeled using Gram-negative bacterial lipopolysaccharide, endotoxin. READ MORE

  4. 4. Antibiotic-induced Bacterial Toxin Release – Inhibition by Protein Synthesis Inhibitors

    Author : Gunilla Hjerdt-Goscinski; Jan Sjölin; Monica Lundholm; Inga Odenholt; Ingrid Nilsson-Ehle; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; Endotoxin; LPS; exotoxin; SpeA; penicillin-binding protein; aminoglycosides; clindamycin; β-lactam antibiotics; severe sepsis; septic shock; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar;

    Abstract : Toxic products, such as endotoxin from the gram-negative and exotoxin from the gram-positive bacteria, are the most important initiators of the inflammatory host response in sepsis. In addition to antibacterial treatment, numerous attempts have been made to interfere with the exaggerated proinflammatory cascade initiated by the toxins. READ MORE

  5. 5. Experimental septic shock – Effects of endotoxemia with special reference to pathophysiological responses in the pig

    Author : Ewa Söderberg; Miklós Lipcsey; Mats B Eriksson; Anders Larsson; Jan Sjölin; Sten Lindahl; Uppsala universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endotoxin; inflammatory response; animal model; timing; steroid treatment; NGAL; Calprotectin; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care;

    Abstract : Sepsis and septic shock are conditions, with severe outcome or in many cases death. Sepsis is a systemic inflammatory response trigger by bacteraemia but systemic inflammatory response can also be triggered by major trauma, major surgery, pancreatitis, severe burns etc. READ MORE