Search for dissertations about: "Endotoxin"

Showing result 11 - 15 of 144 swedish dissertations containing the word Endotoxin.

  1. 11. Regional fluxes of tissue plasminogen activator in porcine endotoxemia

    Author : Annette Nyberg; Göteborgs universitet; []
    Keywords : pig; endotoxin; tissue type plasminogen activator; plasminogen activator inhibitor; tumor necrosis factor ?;

    Abstract : Formation of fibrin clots in the microcirculation during severe sepsis contributes to organ failure, frequently involving the lungs and the splanchnic organs. Tissue type plasminogen activator, tPA, is the key activator of intravascular fibrinolysis with plasminogen activator inhibitor type-1, PAI-1, as its main inhibitor. READ MORE

  2. 12. The temperature-limited fed-batch technique for control of Escherichia coli cultures

    Author : Marie Svensson; Sven-Olof Enfors; John Villadsen; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Endotoxin; Escherichia coli; fed-batch technique; glucose-limitation; mathematical model; Bioengineering; Bioteknik;

    Abstract : The objective of this study was to investigate the physiology and productivity in Escherichia colicultures with emphasis on the temperature-limited fed-batch (TLFB) culture. The TLFB techniquecontrols the oxygen consumption rate of the growing culture by a gradually declining temperaturefrom 37-35 °C down to 20-18 °C. READ MORE

  3. 13. Novel Methods for Sampling, Characterization and Analysis of Airborne Street Particles in a Health Perspective

    Author : Ali Reza Nosratabadi; Anders Ljungman; Per Leandersson; Helen Karlsson; Peter Molnár; Henrik Kylin; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fine; Coarse; wear particles; health; Lead; Cadmium; Brake wear particles; Endotoxin; Interleukins; TEOM; IPRL;

    Abstract : Over the last decades, there has been much attention on air quality, especially in urban environments. A significant factor effecting the air quality in the urban environment is airborne particulate matter (PM). Long-term exposure to PM causes increased risk for heart disease, decreased lung function, exacerbation of asthma, and lung cancer. READ MORE

  4. 14. Nitric oxide in experimental sepsis

    Author : Peter Dahm; Anestesiologi och intensivvård; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; Nitric oxide; Sepsis; NO inhalation; Endotoxin; Acute lung injury; ARDS; Nitric oxide synthase; L-NMMA; L-NAME; Anestesiologi; Anaesthesiology; Pigs; intensivvård;

    Abstract : Nitric oxide (NO) is important in the control of blood pressure and organ perfusion. In septic shock, NO produced by inducible NO-synthase (NOS) has been claimed to mediate pathological vasodilation and cell injury, while NO produced by constitutive NOS may be protective in counteracting hypoperfusion and organ injury. READ MORE

  5. 15. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

    Author : Amro Hanora; Bioteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

    Abstract : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. READ MORE