Search for dissertations about: "Enzyme Unfolding"
Showing result 1 - 5 of 13 swedish dissertations containing the words Enzyme Unfolding.
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1. Stability and inactivation mechanisms of two transaminases
Abstract : In the past decades, more and more enzymes are employed as biocatalysts in industrial processes because of their advantages, such as high efficiency, substrate selectivity and stereoselectivity. Among them, amine transaminases (ATAs) are pyridoxal 5’-phosphate (PLP) dependent enzymes. READ MORE
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2. Angiopoietin-like protein 4 : an unfolding chaperone regulating lipoprotein lipase activity
Abstract : Lipoprotein lipase (LPL) is the main enzyme hydrolyzing triglyceride-rich lipoproteins in plasma. Proteoglycan-bound LPL on the vascular endothelium represent the functional pool of active enzyme. LPL is regulated in a tissue specific manner according to metabolic demands. READ MORE
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3. Computational Studies of the Temperature Dependence of Enzyme Catalysis
Abstract : Enzymes are known to adapt to low temperatures by lowering the enthalpy of activation of the key reaction steps. A lesser known property of some psychrophilic (cold-active) enzymes is an anomalous temperature optimum. READ MORE
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4. Molecular development of a thermostable β-glucosidase for modification of natural products
Abstract : The gene encoding a β-glucosidase originating from the extreme thermophile Thermotoga neopolitana has been cloned and expressed in Escherichia coli. The aim was to produce a thermostable enzyme that could be used to remove sugar residues from glucosylated natural products classified as flavonoids by applying a method combining extraction in hot pressurized water with enzymatic hydrolysis. READ MORE
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5. A thermostable alkaline protease from a new alkaliphilic Nesterenkonia sp
Abstract : This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. READ MORE