Search for dissertations about: "Epithelial barrier function"

Showing result 6 - 10 of 72 swedish dissertations containing the words Epithelial barrier function.

  2. 6. Regulation of Duodenal Mucosal Barrier Function and Motility : The Impact of Melatonin

    Author : Anna Sommansson; Markus Sjöblom; Olof Nylander; Oliver Bachmann; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 51Cr-EDTA; bicarbonate secretion; duodenum; enteric nervous system; enterochromaffin cell; ethanol; hexamethonium; in vivo; mecamylamine; motility; mucosal permeability; parecoxib; rat; Physiology; Fysiologi;

    Abstract : The duodenal mucosa is regularly exposed to acid, digestive enzymes and ingested noxious agents. It is thus critical to maintain a protective barrier to prevent the development of mucosal injury and inflammation, which are often observed in situations when barrier function is impaired. READ MORE

  4. 7. Protein kinase C-dependent regulation of the epithelial barrier

    Author : Anita Sjö; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The intestinal epithelium is essential for the absorption of nutrients and for the defence against harmful substances in the gut. The permeability and barrier functions of epithelia are mainly controlled by the intercellular tight junctions. READ MORE

  5. 8. Intestinal Ischemia and Reperfusion Injury - Pathophysiology as basis for novel treatment

    Author : Zhengwu Sun; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; organ dysfunction; epithelium; endothelium; adhesion molecules; cytokines; protease inhibitor; Intestine; barrier; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

    Abstract : Intestinal ischemia and reperfusion (I/R) is not infrequent in the clinical situation and the intestinal barrier plays an important role in gut barrier function, preventing not at least septic complications and potentially the development of the multiple organ dysfunction syndrome. Mechanisms of intestinal I/R induced gut epithelial and endothelial barrier dysfunction and remote organ dysfunction, as well as potential preventive and therapeutic modes of management were evaluated in the rat. READ MORE

  6. 9. Innate lymphoid cells and cholesterol metabolism in intestinal barrier function

    Author : Sara Martina Parigi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The intestinal mucosa represents one of the largest barrier sites of our body, having to withstand a constant exposure to a plethora of environmental insults (including dietary compounds, xenobiotics, metabolites and microorganisms). While our body has evolved tolerance/ignorance towards some of these factors deemed beneficial for the host, it requires constant maintenance of epithelial barrier integrity and ability to mount pro-inflammatory responses to protect against potentially harmful environmental insults. READ MORE

  7. 10. Tight juntion in ovarian surface epithelium and epithelial ovarian tumors

    Author : Yihong Zhu; Göteborgs universitet; []
    Keywords : junction; claudin; ovarian surface epithelium; epithelial ovarian tumor; TGF-?1;

    Abstract : Epithelial ovarian cancer originating from ovarian surface epithelium (OSE) is the most lethal type of gynecological cancer among women worldwide. The poor understanding of the cellular and molecular events associated with ovarian carcinogenesis leads to difficulties in early diagnosis and in efficient treatment. READ MORE