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Showing result 1 - 5 of 143 swedish dissertations matching the above criteria.

  2. 1. Characterization of non-coding mRNA in Epstein-Barr virus

    Author : Åsa Isaksson; Göteborgs universitet; []
    Keywords : Epstein-Barr virus; EBNA1; IRES; PTLD; alternative splice; nucleotide substitution; protein interactions;

    Abstract : Epstein-Barr virus (EBV) is a human gammaherpesvirus that infects lymphoid and epithelial cells. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disease, and it is additionally associated with various malignancies including Burkitt?s lymphoma, Hodgkin?s disease and lymphoproliferative syndromes in immunocompromised individuals. READ MORE

  4. 2. Functional aspects on the Epstein-Barr virus nuclear antigen 5

    Author : Martin Dufva; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr Virus; EBV; B-cell; transformation; cDNA array; polyadenylation; transcription; cell cycle; apoptosis; two-hybrid system.;

    Abstract : The Epstein-Barr virus (EBV) infects resting B-cells. This leads to an EBV driven transformation of the resting B-cell into a cell with an activated B-cell phenotype that proliferates indefinitely in vitro. Epstein-Barr Nuclear antigen 5 (EBNA5) is one out of six EBV encoded protein involved in transformation of resting B-cell. READ MORE

  5. 3. Nasopharyngeal carcinoma and Epstein-Barr virus

    Author : Li-Fu Hu; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NPC; EBV; EBNAs; LMPI; LMP2; Tumorigenicity; Immunogenicity;

    Abstract : Nasopharyngeal carcinoma (NPC) is the most common tumor in southern China and also quite frequent among the Eskimos and in Alaska. NPC is invariably associated with Epstein-Barr virus (EBV). READ MORE

  6. 4. Posttransplant Lymphoproliferative Disorders : Studies of Epstein-Barr Virus, Regulatory T Cells and Tumor Origin

    Author : Amelie Kinch; Karlis Pauksens; Gunilla Enblad; Eva Baecklund; Harald Holte; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PTLD; Lymphoma; Epstein-Barr Virus; EBV DNAemia; FoxP3; Treg; Microenvironment; Cell of Origin; Recipient; Transplantation; Immunosuppression; Hepatitis C; Survival; Medicinsk vetenskap; Medical Science;

    Abstract : Epstein-Barr virus (EBV) infects almost all humans and establishes lifelong latency in B cells. Posttransplant lymphoproliferative disorder (PTLD) is a rare but serious complication after transplantation triggered by immunosuppression and often related to EBV infection. READ MORE

  7. 5. Regulation of the Epstein-Barr Virus Latent Membrane Protein 1 Expression

    Author : Pegah Johansson; Göteborgs universitet; []
    Keywords : Gene regulation; LMP1; Epstein-Barr virus; Herpesvirus;

    Abstract : Epstein-Barr virus (EBV) is a probably the most effective and successful human virus, infecting more than 90% of the world?s adult population. As with the other members of the herpesvirus family, EBV establishes latent infection in its host and persists life-long. READ MORE