Search for dissertations about: "Epstein-Barr virus"

Showing result 11 - 15 of 143 swedish dissertations containing the words Epstein-Barr virus.

  2. 11. Transcriptional regulation of the Epstein-Barr virus latent membrane protein 1 gene in B cells

    Author : Weiwen Yang; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; LRS; EBNA2; transcription; transactivation; repression; histone deacytylation;

    Abstract : Epstein-Barr Virus (EBV) is a ubiquitous human B-lymphotrobic herpesvirus that latently infects over 90 percent of the world´s population. EBV infection is usually benign in healthy people. READ MORE

  4. 12. Transcriptional regulation of the latent membrane protein 1 gene by Epstein-Barr virus nuclear antigen 2

    Author : Lars Palmqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; B-cell; transformation; LMP1; EBNA2; transcription; phosphorylation; histone acetylation;

    Abstract : The Epstein-Barr virus (EBV) is a ubiquitous human herpes virus, which infects B-cells. This leads to a life-long latent infection, which in most cases is non-pathogenic. However, EBV is etiologically associated with several human malignancies, including endemic Burkitt's lymphoma, nasopharyngeal carcinoma and post-transplant lymphoma. READ MORE

  5. 13. Transcriptional regulation of the Epstein-Barr virus nuclear antigen 1 gene in latent and lytic stages of infection

    Author : Henrik Zetterberg; Göteborgs universitet; []
    Keywords : Epstein-Barr virus; EBNA1; Burkitt s lymphoma; nasopharyngeal carcinoma; ; B-lymphocyte; transformation; transcriptional regulation;

    Abstract : Epstein-Barr virus (EBV) is a lymphotropic herpesvirus that infects more than 90% of humans worldwide. The virus is the causative agent of infectious mononucleosis, a self-limiting lymphoproliferative disorder, and is also associated with a variety of malignancies including Burkitt's lymphoma (BL), Hodgkin's disease (HD), nasopharyngeal carcinoma (NPC), and lymphoproliferative disorders in immunocompromised individuals. READ MORE

  6. 14. The interactome of the Epstein-Barr virus nuclear antigen 5 suggests novel roles in RNA and protein metabolism

    Author : Josefine Ekholm; Göteborgs universitet; []
    Keywords : Epstein-Barr virus; EBNA5; chaperone; proteasome; nucleolus;

    Abstract : Epstein-Barr virus (EBV) is a human herpes virus that infects B and epithelial cells of the oropharynx. EBV is transmitted by saliva and establishes a lifelong latency in over 90% of the world's population. During latency, the virus exists predominantly as multicopy episomes in the nuclei of memory B cells. READ MORE

  7. 15. Control of Epstein-Barr virus infection by cytotoxic T lymphocytes

    Author : Pedro-Otavio de Campos-Lima; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Epstein-Barr virus; Cytotoxic T lymphocytes; T cell receptor; CTLescape mutants;

    Abstract : Cytotoxic T lymphocytes (CTL) play a critical role in response to Epstein-Barr virus (EBV), a widespread human herpes virus that persists in healthy carriers as a latent infection of B cells and is implicated in the pathogenesis of lymphoid and epithelial cell malignancies. Six virus encoded nuclear antigens, EBNA1-6, and three membrane proteins, LMP1, -2A and -2B, are regularly detected in EBV transformed lymphoblastoid cell lines (LCLs). READ MORE