Search for dissertations about: "Erik Sjögren"

Found 2 swedish dissertations containing the words Erik Sjögren.

  1. 1. Hepatic Disposition of Drugs and the Utility of Mechanistic Modelling and Simulation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Erik Sjögren; Uppsala universitet.; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatic disposition; pharmacokinetics; mechanistic modelling; drug-drug interactions; enzyme kinetics; Vmax; Km; CLint; carrier-mediated transport; active transport; modelling; in vitro-in vivo extrapolation; physiologically based pharmacokinetic model; optimal experimental design; experimental optimization; data analysis optimization; PHARMACY; FARMACI; PHARMACY Biopharmacy; FARMACI Biofarmaci; Biopharmaceutics; Biofarmaci;

    Abstract : The elimination of drugs from the body is in many cases performed by the liver. Much could be gained if an accurate prediction of this process could be made early in the development of new drugs. However, for the elimination to occur, the drug molecule needs first to get inside the liver cell. READ MORE

  2. 2. Caring, Sharing, and Childbearing : Essays on Labor Supply, Infant Health, and Family Policies

    University dissertation from Uppsala : Department of Economics, Uppsala University

    Author : Anna Norén; Uppsala universitet.; [2017]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Informal care; Elderly; Labor supply; Alcohol prevention; Brief intervention; AUDIT; Antenatal care; Child health; Childcare; Parental leave; Gender equality; Economics; Nationalekonomi;

    Abstract : Essay I: I study the consequences on labor market outcomes and sick leave of having an elderly parent in need of care. Caring for an elderly parent may be associated with opportunity costs such as productivity loss on the labor market if informal caregivers are of working age. READ MORE