Search for dissertations about: "Ermias Melles"

Found 1 swedish dissertation containing the words Ermias Melles.

2. 1. C-peptide structural and functional relationships studied by biosensor technology and mass spectrometry

   Author : Ermias Melles; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Proinsulin C-peptide; biosensor; mass spectrometry;

   Abstract : Proinsulin C-peptide has a number of biological activities and receives interest focusing on the therapeutic potential as a candidate for future co-replacement therapy with insulin in type 1 diabetes. Based on conservation results from comparisons of 22 mammalian proinsulin variants, analogs were constructed for studies of phosphorylation of mitogenactivated protein kinases (MAPKs) in Swiss 3T3 fibroblasts. READ MORE