Search for dissertations about: "Escherichia coli Infections microbiology"

Showing result 1 - 5 of 29 swedish dissertations containing the words Escherichia coli Infections microbiology.

  2. 1. Antibiotic sensitivity and horizontal gene transfer in Escherichia coli - A genome-wide perspective

    Author : Martin Palm; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; antibiotics; antibiotic resistance; Escherichia coli; heavy metals; bacterial conjugation; pangenome; sub-inhibitory;

    Abstract : Since their discovery in the early 20th century, antibiotics have truly revolutionized human medicine. They have allowed us to treat diseases that were previously untreatable and have become a staple of modern medicine. However, along with the human use of antibiotics pathogens resistant to antibiotics emerged. READ MORE

  4. 2. Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli

    Author : Elisabeth Thulin; Dan I Andersson; Laura Piddock; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mecillinam; Antibiotic resistance; Escherichia coli; Urinary tract infections; Fitness; Penicillin binding proteins; cysteine biosynthesis; Mikrobiologi; Microbiology;

    Abstract : The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. READ MORE

  5. 3. Antibiotic interactions and selection for resistance in biofilms

    Author : Po-Cheng Tang; Dan I. Andersson; Karin Hjort; Mark Webber; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibiotics; Mikrobiologi; Microbiology;

    Abstract : The challenges posed by antibiotic-resistant bacteria in treating infections, particularly those associated with biofilms, require a deeper understanding of this lifestyle and its connection to resistance selection. Additionally, gaining insights into drug interactions is crucial for enhancing combination treatment efficacy and mitigating resistance development. READ MORE

  6. 4. The efficacy of bacterial viruses against multi-resistant Escherichia coli: from isolation to pharmacology

    Author : Mohammadali Khan Mirzaei; Anders Nilsson; Rob Lavigne; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Phage therapy; Multiresistant E. coli; Pharmacodynamics; Pharmacokinetics; Bacterial viruses; Genomic; proteomic; molekylärgenetik; Molecular Genetics;

    Abstract : The increase of multi-resistant bacteria highlights that the golden era of antibiotics is ending and that alternative treatmentsare urgently needed. Phages have been historically used to treat bacterial infections prior to the discovery of antibiotics and have gained renewed interest in the past decade. READ MORE

  7. 5. Evolution and Mechanisms of Tigecycline Resistance in Escherichia coli

    Author : Marius Linkevičius; Dan I. Andersson; Linus Sandegren; Patrice Courvalin; Uppsala universitet; []
    Keywords : Tigecycline; Bacterial resistance; Fitness; Escherichia coli; AcrAB; LPS; Tet proteins; Tet A ; Tet K ; Tet M ; Tet X ; tet genes; pUUH239.2; Mikrobiologi; Microbiology;

    Abstract : Antibiotic resistance is an ongoing global medical crisis and we are in great need of new antibacterial agents to combat rapidly emerging resistant pathogens. Tigecycline is one of few drugs that have been introduced into medicine during the last two decades. READ MORE