Search for dissertations about: "Escherichia-coli strains"

Showing result 1 - 5 of 132 swedish dissertations containing the words Escherichia-coli strains.

  1. 1. Study of phages for phage therapy : An Escherichia coli experience

    Author : Mohammadali Khan Mirzaei; Anders Nilsson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; molekylärgenetik; Molecular Genetics;

    Abstract : The world is rapidly moving toward a post-antibiotic era as effective antibiotics are becoming fewer. phage therapy is a potentially possible method for treating infectious diseases and counts as an alternative method for antibiotic therapy. READ MORE

  2. 2. Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae : Treatment, Selection and International Spread

    Author : Thomas Tängdén; Otto Cars; Anders Johansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Escherichia coli; Klebsiella pneumoniae; extended-spectrum beta-lactamases; carbapenemases; metallo-beta-lactamases; synergy; antibiotic interventions;

    Abstract : The prevalence of Escherichia coli and Klebsiella pneumoniae producing extended-spectrum beta-lactamases (ESBLs) and carbapenemases is increasing worldwide. Therapeutic options for infections with these bacteria are limited not only by the production of ESBLs and carbapenemases, which confer resistance to cephalosporins and carbapenems, but also by frequent co-resistance to other antibiotics. READ MORE

  3. 3. Into the Membrane and Beyond : Improving Membrane Protein Over-Expression in Escherichia coli

    Author : Mirjam Klepsch; Jan-Willem de Gier; Reinhard Grisshammer; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Escherichia coli; membrane protein over-expression; proteomics; T7 RNA polymerase; peptide transport; strain engineering; Biochemistry; Biokemi; Biophysical chemistry; Biofysikalisk kemi; biokemi; Biochemistry;

    Abstract : Membrane proteins fulfil a wide variety of essential functions in the cell and many are (potential) drug targets. Since their natural abundance is usually very low, most membrane proteins have to be over-expressed for functional and structural studies. READ MORE

  4. 4. Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli

    Author : Elisabeth Thulin; Dan I Andersson; Laura Piddock; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mecillinam; Antibiotic resistance; Escherichia coli; Urinary tract infections; Fitness; Penicillin binding proteins; cysteine biosynthesis; Mikrobiologi; Microbiology;

    Abstract : The introduction of antibiotics in healthcare is one of the most important medical achievements with regard to reducing human morbidity and mortality. However, bacterial pathogens have acquired antibiotic resistance at an increasing rate, and due to a high prevalence of resistance to some antibiotics they can no longer be used therapeutically. READ MORE

  5. 5. Probing Control of Glucose Feeding in Escherichia coli Cultivations

    Author : Mats Åkesson; Institutionen för reglerteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Automatiska system; control engineering; robotics; Automation; dissolved oxygen; acetate; glucose feeding; robotteknik; Escherichia coli; Process control; fed-batch cultivation; reglerteknik; Biotechnology; Bioteknik;

    Abstract : Production of many proteins can today be made using genetically modified organisms. One of the most frequently used host organisms is the bacterium Escherichia coli. A difficulty encountered in cultivations of E. coli is the accumulation of the metabolic by-product acetate which inhibits cell growth and production of a desired protein. READ MORE