Search for dissertations about: "Esophageal adenocarcinoma"

Showing result 1 - 5 of 32 swedish dissertations containing the words Esophageal adenocarcinoma.

  1. 1. Prognostic role of the tumour microenvironment in esophago-gastric, pancreatic and periampullary adenocarcinoma: B cells and beyond

    Author : Richard Fristedt; Tumörmikromiljö; []
    Keywords : Polymeric immunoglobulin receptor; B cells; Plasma cells; Esophageal adenocarcinoma; gastric adenocarcinoma; Pancreatic ductal adenocarcinoma; Periampullary adenocarcinoma; Prognosis and survival; Immune system;

    Abstract : Cancer development depends on cells aquiring a skillset of limitless growth and finally invasive properties to allow for metastasis, as summarised by the six hallmarks of cancer. Recently four more hallmarks have been added: genomic instability, deregulating cellular metabolism, tumour-promoting inflammation and avoiding immune destruction. READ MORE

  2. 2. The tumor immune microenvironment and clinical outcome in patients with esophageal and gastric adenocarcinoma

    Author : Maria C Svensson; Personlig patologi och cancerbehandling; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin och hälsovetenskap; tumor immune microenironment; Esophageal cancer; Gastric cancer; prognosis; Prediction; Adenocarcinoma; T cells; B cells; NK cells; tumor-associated macrophage TAM ; PD-L1; PD-1;

    Abstract : .... READ MORE

  3. 3. Predictive Factors in Esophageal Carcinoma

    Author : Martin Dreilich; Michael Bergqvist; Anders Larsson; Daniel Brattström; Gunnar Wagenius; Claes Mercke; Uppsala universitet; []
    Keywords : Oncology; Esophageal carcinoma; Survival; Prognosis; Angiogenesis; HER-2; Telomerase; FMCA; HPV; Onkologi;

    Abstract : Esophageal carcinoma is a malignancy with a poor prognosis and is the sixth cause of cancer related death worldwide. In Sweden approximately 400 new cases are diagnosed every year. The aim of this present thesis was to investigate predictive factors for esophageal carcinoma patients. READ MORE

  4. 4. Towards improved oncological treatment of esophageal and gastric cancer. Clinical and translational studies

    Author : David Borg; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal adenocarcinoma; Gastric cancer; PODXL; Prognosis; Prediction; Chemotherapy dose intensity; Dysphagia; Radiotherapy;

    Abstract : BackgroundThe overall aim of this thesis was to improve the oncological treatment strategies in esophageal and gastric adenocarcinoma (EGAC). Podocalyxin-like protein 1 (PODXL) has been associated with poor prognosis in other cancers and we wanted to investigate its potential role as a prognostic and predictive biomarker in resectable EGAC. READ MORE

  5. 5. Estrogen in the development of esophageal and gastric adenocarcinoma

    Author : Evangelos Chandanos; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to address the hypothesis that estrogen protects women against the development of esophageal and gastric adenocarcinoma (AC). These two cancers show a striking but totally unexplained male predominance in their incidence. READ MORE