Search for dissertations about: "Eszter Somogyi-ganss"

Found 1 swedish dissertation containing the words Eszter Somogyi-ganss.

2. 1. Novel non-collagenous modulators of biomineralization in bone and dentin

   Author : Eszter Somogyi-Ganss; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Calreticulin; nucleobindin; prothrombin; biomineralization; osteogenesis; dentinogenesis;

   Abstract : The formation of mineralized tissues such as bones and teeth is governed on many levels by molecular, genetic, and cellular events to culminate in terminally differentiated cells that secrete a specialized organic matrix, which is later mineralized through the coordinated deposition of calcium phosphate crystals. The formation of this hard tissue phase is tightly regulated by components of the extracellular matrix (ECM), since deviations from this equilibrium result in prevalent, debilitating health problems such as arthritis, vascular calcification, periodontal disease and osteoporosis. READ MORE