Search for dissertations about: "Etienne P.A. Neve"

Found 1 swedish dissertation containing the words Etienne P.A. Neve.

2. 1. Molecular basis and structural determinants for the cellular localization of cytochrome P450 2E1

   Author : Etienne P A Neve; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Cytochrome P450 2E1 (CYP2E1) is the alcohol inducible member of the P450 family and has a role in gluconeogenesis under fasting conditions. However, CYP2E1 is mainly of toxicological significance and metabolizes xenobiotics to their carcinogenic and toxic metabolites and generates active oxygen species that can cause lipid peroxidation and apoptosis, processes observed in alcoholic liver disease (ALD). READ MORE