Search for dissertations about: "Eva Dahlén"

Found 1 swedish dissertation containing the words Eva Dahlén.

2. 1. Antigen presenting cells in autoimmune diabetes: phenotype, function and modulation by Linomide

   Author : Eva Dahlén; Lunds universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; secreting systems; Endocrinology; Linomide; costimulation; TNF-a; dendritic cells; Diabetes; macrophages; diabetology; Endokrinologi; sekretion; diabetologi; Immunology; serology; transplantation; Immunologi; serologi;

   Abstract : The aim of this thesis was to better understand the role of antigen presenting cells (APC) in the development of diabetes in the nonobese diabetic (NOD) mouse. We have shown that DC and Mphi that infiltrate the islets of Langerhans produce tumour necrosis factor-a (TNF-a), a cytokine known to contribute to the pathogenesis in the early stages of diabetes development. READ MORE