Search for dissertations about: "Evaluation of biomarkers in chronic"

Showing result 1 - 5 of 15 swedish dissertations containing the words Evaluation of biomarkers in chronic.

  2. 1. Evaluation of biomarkers in chronic inflammatory diseases

    Author : Zahra Golabkesh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The overall aim of this thesis was to assess the role of biomarkers in chronic inflammatory disease. The goal of the first study was to investigate the association of sIL-6R and sgp130 levels and risk of first myocardial infarction (MI), and to explore the potential interaction between these two biomarkers in association with risk of MI. READ MORE

  4. 2. The pain profile in fibromyalgia : Painomic studies of pain characteristics and proteins in blood

    Author : Karin Wåhlén; Bijar Ghafouri; Björn Gerdle; Mika Gustafsson; Manuela Schmidt; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Chronic widespread pain (CWP), including fibromyalgia (FM), is a complex pain condition, where little is known about the molecular mechanisms contributing to its pathophysiology. To date, there are no established biomarkers for CWP/FM. READ MORE

  5. 3. Studies of the Biology of Intrathecal Treatment in Progressive MS

    Author : Joakim Bergman; Anders Svenningsson; A. Tommy Bergenheim; Jonathan D. Gilthorpe; Joachim Burman; Magnus Andersson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Progressive Multiple Sclerosis; intrathecal treatment; Ommaya reservoir; anti-CD20 therapy; microdialysis; cerebrospinal fluid; CNS compartments; Progressiv Multipel Skleros; intratekal behandling; Ommaya reservoar; anti-CD20 terapi; mikrodialys; ryggmärgsvätska; sektioner i centrala nervsystemet; Neurology; neurologi;

    Abstract : Background: Multiple Sclerosis (MS) is a chronic, inflammatory, autoimmune disease, affecting the central nervous system (CNS). About 85% of afflicted present with a relapsing-remitting form of the disease (RRMS), for which a breakthrough in treatment was made in 2008 with rituximab, an antibody directed towards CD20, a surface antigen on B-cells. READ MORE

  6. 4. Endocannabinoids and Related Lipids in Chronic Pain : Analytical and Clinical Aspects

    Author : Niclas Stensson; Bijar Ghafouri; Björn Gerdle; Nazdar Ghafouri; Christopher Fowler; Per-Johan Jakobsson; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : In Europe, approximately one in five adults experience chronic pain, pain that lasts more than three months. Chronic pain is a significant problem not only for those people suffering from chronic pain but also for society. The prevalence of chronic pain is higher in women and lower socioeconomic groups. READ MORE

  7. 5. Phenotyping of severe asthma in a clinical context

    Author : Valentyna Yasinska; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Severe asthma is a chronic heterogeneous inflammatory disease characterized by several clinical phenotypes and molecular endotypes. Although it affects a relatively small proportion of the asthma population (approximately 4%-10%), with an even smaller proportion of these having severe uncontrolled eosinophilic asthma, it accounts for > 50% of the costs attributed to the disease. READ MORE