Search for dissertations about: "Evan’s alkylation"

Found 2 swedish dissertations containing the words Evan’s alkylation.

  2. 1. Asymmetric Synthesis of C-Glycosylated Amino Acids : Incorporation in Collagen Glycopeptides and Evaluation in a Model for Rheumatoid Arthritis

    Author : Tomas Gustafsson; Jan Kihlberg; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Total synthesis; stereoselective synthesis; chiral glycine templates; Evan’s alkylation; asymmetric hydrogenation; alpha-amino acid synthesis; C-glycoside; rheumatoid arthritis; MHC; T cell; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes stereoselective syntheses of four amino acids, three of which are C-glycosidic analogues of glycosylated amino acids. The overall goal of the project was to probe the interactions between MHC molecules, glycopeptide antigens and T cell receptors, that are essential for development of collagen induced arthritis. READ MORE

  4. 2. MECHANISTIC INVESTIGATIONS OF TRANSITION METAL CATALYZED REACTIONS

    Author : Jonatan Kleimark; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; alkene insertion; allylic alkylation; catalysis; cross coupling; density funtional theory; free energy surface; iron; kinetic investigation; Mizoroki-Heck reaction; nickel; palladium; reaction mechanism; sulfinylation; transition metal;

    Abstract : Transition metal catalyzed reactions have had a large impact on the human progress for the last century. Several extremely important areas, such as the agricultural industry and the plastic industry, have benefited from this development. READ MORE