Search for dissertations about: "Evolution and transcriptome."

Showing result 1 - 5 of 38 swedish dissertations containing the words Evolution and transcriptome..

  2. 1. Genome and Transcriptome Comparisons between Human and Chimpanzee

    Author : Anna Wetterbom; Ulf Gyllensten; Lucia Cavelier; Tomas Bergström; Evan Eichler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human; chimpanzee; genome; transcriptome; comparative studies; exon arrays; next-generation sequencing; premature termination codon; alternative splicing; primate evolution; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; Bioinformatik; Bioinformatics;

    Abstract : The chimpanzee is humankind’s closest living relative and the two species diverged ~6 million years ago. Comparative studies of the human and chimpanzee genomes and transcriptomes are of great interest to understand the molecular mechanisms of speciation and the development of species-specific traits. READ MORE

  4. 2. Conifer Evolution, from Demography and Local Adaptation to Evolutionary Rates : Examples from the Picea genus

    Author : Jun Chen; Martin Lascoux; Ulf Lagercrantz; Matt Olson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Speciation; Demographics; clinal variation; convergent evolution; transcriptome; small regulatory RNA; Biologi med inriktning mot evolutionär funktionsgenomik; Biology with specialization in Evolutionary Functional Genomics; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Evolutionary process can be inferred at three different levels: the species level, the population level and the molecular level. In this thesis, I applied approaches at these three levels and aimed to get a comprehensive picture of conifer evolution, from speciation and demography to geographic variation and local adaptation, and then to the molecular evolution of proteins and small regulatory RNAs. READ MORE

  5. 3. Statistics in Gene Expression, Metabolomics, and Comparative Genomics in Evolution

    Author : Alexandra Jauhiainen; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gene Expression; Metabolomics; Data Integration; Comparative genomics; Gene Expression;

    Abstract : This thesis contains four papers concerning (I) the evolutionary conservation of drug targets and its potential use in environmental risk assessments, (II) RNA degradation as a control mechanism during osmotic stress in the yeast S. cerevisiae, (III) the localization and effects of the gene DDIT3 encoding a key regulator of stress response, and (IV) the integration and analysis of transcriptional and metabolic data to identify active metabolic pathways. READ MORE

  6. 4. Function and Evolution of Small Regulatory RNAs and their Associated Proteins : A Journey from Genome to Proteome

    Author : Bart Edelbroek; Fredrik Söderbom; Jonathan R. Chubb; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microRNAs; non-coding RNAs; Evolution; Whole Genome Sequencing; Transcriptomics; Proteomics; small RNAseq; Amoebozoa; Multicellular development; Social amoebae; Comparative genomics; Genome annotation; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Abstract : Organisms throughout the tree of life have evolved distinct ways to regulate gene expression. Some of these processes involve non-coding RNAs (ncRNAs), which are not translated but functional nonetheless. These ncRNAs are of utmost importance, with dysregulation of some causing severe developmental effects or even being lethal. READ MORE

  7. 5. Evolution of olfaction in Lepidoptera and Trichoptera : Gene families and antennal morphology

    Author : Jothi Kumar Yuvaraj; Funktionell zoologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; evolution; pheromone receptors; olfaction; chemosensory; sensillum; HEK 293 cells;

    Abstract : In moths, females produce sex pheromone compounds to attract males over a long distance for mating. The antennae of moths and many other insects have specialized odorant receptors (ORs), called pheromone receptors (PRs), to sense the pheromone compounds and they group in a monophyletic clade (PR clade). READ MORE