Search for dissertations about: "Exons"
Showing result 1 - 5 of 123 swedish dissertations containing the word Exons.
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1. Structure and organization of genes for the predominant seminal plasma proteins semenogelin I, semenogelin II and beta-microseminoprotein
Abstract : In man, the predominant proteins in the seminal plasma include semenogelin I, semenogelin II and b-microseminoprotein (MSP). Semenogelin I and II are both synthesized in the seminal vesicles and are the backbone of the gel formed upon semen coagulation. MSP is synthesized in the prostate, but its role has not yet been defined. READ MORE
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2. Molecular studies in different types of melanoma tumors : correlations to clinical data
Abstract : Approximately 90% of melanomas arise from skin sites (known as cutaneous malignant melanoma; CMM), whereas the non-cutaneous melanoma (mucosal and ocular melanomas) are rare, accounting for about 10%. Familial melanoma accounts for up to 10% of patients diagnosed with CMM. Both genetics (e.g. READ MORE
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3. Human glycogen synthase genes. Role in insulin resistance and hypoglycaemia
Abstract : Effective insulin-stimulated storage of excess glucose after a meal, and its rapid mobilisation in the fasting state provide basis of glucose homeostasis. Glycogen is the macromolecular storage form of glucose and glycogen synthase (GS) is the rate-limiting enzyme in glycogen synthesis. Skeletal muscle and liver are the major depots of glycogen. READ MORE
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4. Hormone-sensitive lipase: Molecular analyses of the human gene; structural and evolutionary aspects on expression, alternative splicing and cold adaptation
Abstract : Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. READ MORE
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5. The Nucleosome as a Signal Carrying Unit : From Experimental Data to Combinatorial Models of Transcriptional Control
Abstract : The human genome consists of over 3 billion nucleotides and would be around 2 meters long if uncoiled and laid out. Each human somatic cell contains all this in their nucleus which is only around 5 µm across. This extreme compaction is largely achieved by wrapping the DNA around a histone octamer, the nucleosome. READ MORE