Search for dissertations about: "Extracellular matrix"

Showing result 26 - 30 of 555 swedish dissertations containing the words Extracellular matrix.

  2. 26. Collagen of the extracellular matrix. Functional and structural studies

    Author : Olof Olsson; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Collagen; Extra Cellular Matrix. TGF-beta; integrin αvβ6;

    Abstract : The cancer microenvironment has been attracting increasing attention as the realization of its importance for both disease treatment and malignant progression. Here the aim was to elucidate some of the effects and mechanisms of the tumor microenvironment related to the extracellular matrix (ECM). READ MORE

  4. 27. Bacterial interaction with the fibrinolytic system and extracellular matrix

    Author : Thomas Herrman Eberhard; Karolinska Institutet; Karolinska Institutet; []
    Keywords : plasminogen; extracellular matrix; basement membrane; virulence factors; fibronectin; vitronectin; collagen; Haemophilus influenzae Neisseria meningitidis Streptococcus pneumoniae;

    Abstract : Bacterial infection of host organisms is a state of complex interaction between the parasite and the host. Two critical steps in the infectious process are: Adhesion to the epithelial surfaces and penetration of tissue barriers to gain entrance to tissues and into the circulation. These two steps have been the subjects of this thesis. READ MORE

  5. 28. Engineering the extracellular matrix to model diseases and orchestrate regeneration

    Author : Zackarias Söderlund; Lungbiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The extracellular matrix is not only a scaffold to which cells attach, but it is also a matrix that communicates cell signals. Because of the interplay between cells and the extracellular matrix, changes in the extracellular matrix can steer cell fate. READ MORE

  6. 29. Decellularized liver extracellular matrix as a 3D scaffold for bioengineering applications

    Author : Vamakshi Khati; Aman Russom; Håkan Jönsson; Giulia Gaudenzi; Ana Teixeira; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; liver decellularization; decellularized liver matrix bioink; bioprinting; sacrificial scaffold; viscoelasticity; bioengineering; tumor modeling; stem cell differentiation; bioreactor; Biotechnology; Bioteknologi;

    Abstract : The increasing global burden of end-stage liver disease has increased the need for liver transplantation, the definitive cure. However, there is a huge discrepancy between the number of available organ donors and the number of patients waiting for transplantation, resulting in the deaths of a significant number of patients on the waiting list as only 10% of the global need for transplantation is met. READ MORE

  7. 30. Immune Responses Aginst Aldehyde Modified Extracellular Matrix in Atherosclerosis

    Author : Pontus Dunér; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PlaqueMalondialdehydeAtherosclerosisAutoantibodiesExtracellular MatrixFibronectinLamininoxidized LDLT regulatory cellsAlum;

    Abstract : Atherosclerosis is a chronic inflammatory disease and the leading cause of myocardial infarction and stroke. Accumulation, aggregation and subsequent oxidation of LDL in the arterial wall are considered as key events in the development of atherosclerosis. READ MORE