Search for dissertations about: "Extracellular vesicles"

Showing result 21 - 25 of 124 swedish dissertations containing the words Extracellular vesicles.

  2. 21. Analysis of extracellular vesicles and their application in immunotherapy

    Author : Rosanne E Veerman; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Extracellular Vesicles (EVs) are nano-sized particles secreted by most, if not all, cell types. They are important mediators in intercellular communication and carry a broad array of biomolecules such as lipids, nucleic acids and proteins. READ MORE

  4. 22. Micro-RNA: The “Micro”-managers of cardiovascular diseases - Role of extracellular vesicles-mediated miRNAs in cardiovascular diseases

    Author : Kreema James; Kardiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiology; molecular biology; extracelluar vesicles; Micro-RNA; Protein;

    Abstract : Cardiovascular disease (CVD) is the leading cause of death globally, impacted by both extrinsic and intrinsic factors. The disease at the molecular level, however, is governed by inflammation and characterized by endothelial dysfunction. READ MORE

  5. 23. Mechanistic studies on the role of extracellular vesicles in the tumor microenvironment

    Author : Helena Christianson; Tumörmikromiljö; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; microvesicle; exosome; Key words Extracellular vesicle; glioblastoma; hypoxia; angiogenesis; acidosis; proteoglycan; endocytosis; carbonic anhydrase IX; biomarker.;

    Abstract : The transition from normal into malignant cells with acquired uncontrolled growth is a process where cancer cells viciously develop adaptive strategies to overcome microenvironmental and metabolic stress. Hypoxia, or deficient oxygen supply, is a common feature of the expanding tumor which alters cell metabolism and consecutively causes lowered intracellular pH. READ MORE

  6. 24. Epithelial signatures in respiratory disease

    Author : Elisabeth Ax; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; inflammation; gene expression; extracellular vesicles; miRNA;

    Abstract : The epithelium of the human airways protects us against harm and helps maintain immune homeostasis. In respiratory diseases such as asthma and COPD, the functions of the epithelium are altered and can cause or contribute to disease progression. READ MORE

  7. 25. Pathophysiological role and therapeutic potential of extracellular vesicles in cancer

    Author : Doste Mamand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Extracellular vesicles (EVs) are nanosized lipid bilayer vesicles that are endogenously generated through various biogenesis pathways within most cellular entities. Subsequently, they are released into the extracellular milieu to facilitate intercellular communication. READ MORE