Advanced search

Showing result 1 - 5 of 7 swedish dissertations matching the above criteria.

2. 1. Measurement and Evaluation of Antioxidant Status and Relation to Oxidative Stress in Humans

   Author : Cecilia Nälsén; Bengt Vessby; Margareta Öhrvall; Lars Ove Dragsted; Uppsala universitet; []
   Keywords : Nutrition; antioxidant; antioxidant status; antioxidant capacity; oxidative stress; lipid peroxidation; F2-isoprostanes; dietary factors; vitamin E; n-3 fatty acids; human; Näringslära;

   Abstract : Numerous diseases are associated with reduced antioxidant defence and oxidative stress. The antioxidant defence includes dietary and endogenous antioxidants and involves complex interactions between them. READ MORE

4. 2. Homocysteine and Coronary Artery Disease With special Reference to Biochemical Effects Of Vitamin Therapy

   Author : Torfi Jonasson; Kardiologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; pyridoxine.; oxidative stress; lipid peroxidation; inflammation; homocysteine; endothelial function; folate; F2-isoprostanes; cystatine C; Acut coronary syndrome; cardiovascular disease; asymmetric dimethylarginine; cobalamine;

   Abstract : An elevated plasma level of homocysteine has been suggested as a risk factor for cardiovascular disease. The objectives of this thesis were to study the influence of renal function on homocysteine levels in patients with coronary artery disease and to explore the association of elevated plasma levels of homocysteine to oxidative stress, inflammation, and endothelial dysfunction. READ MORE

5. 3. Oxidative Stress, Angiogenesis and Inflammation in Normal Pregnancy and Postpartum

   Author : Maria Palm; Ove Axelsson; Samar Basu; Charlotta Grunewald; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Angiogenesis; inflammation; IL-6; F2-isoprostanes; oxidative stress; Pentraxin 3; PGF2α; PlGF; pregnancy; sFlt1; TNF-α; VEGF-A; Obstetrik och gynekologi; Obstetrics and Gynaecology; Medicinsk vetenskap; Medical Science;

   Abstract : The aims were to investigate oxidative stress (I), angiogenesis (II) and inflammation (III-IV) in healthy women during pregnancy and postpartum. Oxidative stress was estimated by measurement of 8-iso-PGF2α and the antioxidants α- and γ-tocopherol. READ MORE

6. 4. Lipid peroxidation in vivo : Evaluation and application of methods for measurement

   Author : Eva Södergren; Uppsala universitet; []
   Keywords : Medical sciences; lipid peroxidation; hydroperoxides; F2-isoprostanes; MDA; prostaglandins; measurement; carbon tetrachloride; vitamin E; dietary fat quality; rapeseed oil; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Geriatrics; geriatrik;

   Abstract : Lipid peroxidation is thought to be an important factor in the pathophysiology of a number of diseases and in the process of ageing, but its measurement in vivo has been difficult. The aim of this thesis was to evaluate methods for measurement of lipid peroxidation in vivo that are suitable for clinical investigations, and to apply these methods in animal and human studies investigating basal conditions and situations associated with increased lipid peroxidation. READ MORE

7. 5. Lung mechanics and airway inflammation in murine models of asthma

   Author : Sofia Jonasson; Josephine Hjoberg; Hedenstierna Göran; Carl Persson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; airway inflammation; murine models; lung mechanics; forced oscillation technique; airway reactivity; deep inhalations; oxidative stress; nitric oxide; glucocorticoids.; Clinical physiology; Klinisk fysiologi; klinisk fysiologi; Clinical Physiology;

   Abstract : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). READ MORE