Search for dissertations about: "FARMACI Biologisk beroendeforskning"

Showing result 1 - 5 of 9 swedish dissertations containing the words FARMACI Biologisk beroendeforskning.

  1. 1. Levodopa- and Neuroleptic-Induced Dyskinesias Studies on Pharmacological Modification and Processing of Opioid Neuropeptides

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Rebecka Klintenberg; Uppsala universitet.; [2003]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Opioid peptides; dyskinesia; Parkinson s disease; mass spectrometry; metabolism; Biologisk beroendeforskning; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning; biologisk beroendeforskning; Biological Research on Drug Dependence;

    Abstract : Dyskinesias or abnormal involuntary movements are a debilitating complication of long-term levodopa treatment of Parkinson’s disease (PD) that is widely experienced and may compromise the efficacy of the drug therapy. Tardive dyskinesia is another important adverse effect seen with antipsychotic drug treatment. READ MORE

  2. 2. Preproenkephalin Gene and mRNA Studies of Structure, Function, Cocaine Responses in an Animal Model, and Genetic Association with Human Opiate Addiction

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Karl Steven LaForge; Uppsala universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Neuropeptides; Endogenous opioid system; Drug addiction; Heroin; Cocaine; Gene expression; Genetic association; Biologisk beroendeforskning; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning;

    Abstract : The endogenous opioid enkephalin neuropeptides are mediators of pain perception and have been implicated in human addictions. The preproenkephalin gene and its mRNA have also provided many examples of tissue- and species-specific variations in mRNA structure produced through a variety of transcriptional and post-transcriptional mechanisms. READ MORE

  3. 3. Anabolic Androgenic Steroids Effects on Neuropeptide Systems in the Rat Brain

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mathias Hallberg; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biological research on drug dependence; Anabolic androgenic steroids; Nandrolone decanoate; Substance P; NK1 receptor; Substance P 1-7 ; Endopeptidase; Opioids; Calcitonin gene-related peptide; Radioimmunoassay; Autoradiography; Central nervous system; Rats; Biologisk beroendeforskning; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning;

    Abstract : Anabolic-androgenic steroids (AAS) have been used in clinics for decades. The misuse of AAS has previously been attributed merely to sport athletes, taking AAS with intentions to increase muscle mass, enhance physical performance and to improve results in competitions. READ MORE

  4. 4. The Impact of Nandrolone Decanoate on Neuropeptidergic Mechanisms Related to Cognition, Aggression, Reward and Dependence

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kristina Magnusson; Uppsala universitet.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anabolic androgenic steroids; Nandrolone decanoate; Substance P; Dynorphin A; KOP receptor; Prodynorphin; Radioimmunoassay; Autoradiography; Morris water maze; PCR; Central nervous system; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning; Biological Research on Drug Dependence; Biologisk beroendeforskning;

    Abstract : The abuse of anabolic androgenic steroids (AAS) is becoming increasingly common and may result in a range of physiological as well as psychological effects such as altered behavior in terms of increased aggression, cognitive dysfunction and addictive behavior. AAS comprise testosterone and its derivatives, of which nandrolone is one of the more common. READ MORE

  5. 5. Characterization of Substance P (SP) Aminoterminal SP (1-7) Binding in Brain Regions and Spinal Cord of the Male Rat Studies on the Interaction with Opioid Related Pathways

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Milad Botros; Uppsala universitet.; [2008]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY Biological research on drug dependence; FARMACI Biologisk beroendeforskning;

    Abstract : Binding sites for substance P(1-7), SP(1-7) have been identified and characterized for the first time in crude membrane fraction from rat CNS using tritiated ([3H]) SP(1-7) as tracer. These putative receptors were investigated in relation to their affinity for tachykinins, opioid peptides and sigma receptor ligands. READ MORE