Search for dissertations about: "FARMACI"
Showing result 1 - 5 of 605 swedish dissertations containing the word FARMACI.
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1. In vitro and in silico prediction of drug-drug interactions with transport proteins
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Drug transport across cells and cell membranes in the human body is crucial for the pharmacological effect of drugs. Active transport governed by transport proteins plays an important role in this process. A vast number of transport proteins with a wide tissue distribution have been identified during the last 15 years. READ MORE
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2. Engineering of Pharmaceutical Particles Modulation of Particle Structural Properties, Solid-State Stability and Tabletting Behaviour by the Drying Process
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Relationships between stresses during the drying process, particle structural and functional properties, and particle engineering by the drying process were addressed in this thesis. In the first part, the importance of the drying phase and the effect of the drying rate on the intragranular porosity of microcrystalline cellulose pellets were investigated. READ MORE
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3. New Concepts in Administration of Drugs in Tablet Form Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. READ MORE
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4. Mucosal Vaccination Using Polyacryl Starch Microparticles as Adjuvant with Salmonella enteritidis as a Model Pathogen
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Polyacryl starch microparticles have been developed as a new mucosal vaccine adjuvant intended for use in oral vaccination. The main objectives of this thesis were to evaluate the efficacy of these polyacryl starch microparticles and to study their uptake through mucosal tissues. READ MORE
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5. New Approaches to Studies of Paracellular Drug Transport in Intestinal Epithelial Cell Monolayers
University dissertation from Uppsala : Acta Universitatis UpsaliensisAbstract : Studies of intestinal drug permeability have traditionally been performed in the colon-derived Caco-2 cell model. However, the permeability of these cell monolayers resembles that of the colon rather than that of the small intestine, which is the major site of drug absorption following oral administration. READ MORE
