Search for dissertations about: "FEP"

Showing result 1 - 5 of 16 swedish dissertations containing the word FEP.

  1. 1. Theoretical studies of protein-ligand binding

    University dissertation from Lund University (Media-Tryck)

    Author : Majda Misini Ignjatovic; Lunds universitet.; Lund University.; [2019-06-05]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein-ligand binding; MD; GIST; GCMC; FEP; Solvation; Entropy; Water; QM MM-FEP; Protein-ligand binding; MD; GIST; GCMC; FEP; Solvation; Entropy; Water; QM MM-FEP;

    Abstract : Understanding how drugs work is of great importance, since it can facilitate drug discovery, both time- and costwise. At the same time, it is important to have methods that can help predict how well does a potential drug molecule bind to its target. Computational methods can in many ways contribute to drug design process. READ MORE

  2. 2. Assessment of Computational Methods for Ligand Binding

    University dissertation from Division of Theoretical Chemistry, Department of Chemistry, Lund University

    Author : Paulius Mikulskis; Lunds universitet.; Lund University.; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; binding affinities; MM GBSA; MM PBSA; LIE; FEP; TI; BAR; protein-ligand complexes; drug design;

    Abstract : Popular Abstract in English Proteins are a big biological molecules that help cells to function. Proteins play important roles in all vital processes of the living cell, transporting molecules, speeding up chemical reactions, supporting structure of other proteins and the cell, helping the cell to move. Various disease-causing agents (e.g. READ MORE

  3. 3. Transport Properties and Durability of LCP and FRP materials for process equipment

    University dissertation from Stockholm : KTH

    Author : Stefanie Römhild; KTH.; [2010]
    Keywords : Liquid crystalline polymer LCP ; Vectra A950; disclination; annealing; transport properties; diffusion; lining; bonding; glass fibre reinforced plastics FRP ; thermoset; vinyl ester; novolac; water; water activity; sorption isotherm; long-term properties; FEP;

    Abstract : This thesis focuses on transport properties and durability of liquid crystalline polymers (LCP)and fibre reinforced plastics (FRP) with regard to application in industrial process equipment.In the first part of the study the possibility of using a thermotropic LCP of type Vectra A950as lining material for FRP process equipment was investigated. READ MORE

  4. 4. Deciphering the interplay between peripheral and central cytokine- and kynurenine pathways : importance for the pathophysiology of schizophrenia

    University dissertation from Stockholm : Karolinska Institutet, Dept of Physiology and Pharmacology

    Author : Funda Orhan; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Growing evidence suggests a role of low-grade inflammation in the pathophysiology of schizophrenia, giving rise to a dysregulation in neurons containing dopamine and glutamate as well as γ-aminobutyric acid (GABA). In this thesis, a role of peripheral and brain-immune signaling molecules, as well as brain neurotransmitters, was investigated in a wellcharacterized cohort of first-episode psychosis (FEP) patients. READ MORE

  5. 5. Neuropsychological Aspects of First-Episode Psychosis - Diagnosis, Course and Outcome

    University dissertation from Lund University

    Author : Roger Carlsson; Lunds universitet.; Lund University.; [2010]
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; cognitive functions; neuropsychology; First Episode Psychosis; schizophrenia; outcome; predictors;

    Abstract : Popular Abstract in Swedish Föreliggande avhandling syftar till att närmare undersöka neuropsykologiska funktioner hos patienter med psykossjukdom och baseras på fyra studier avseende förstagångsinsjuknade patienter i psykos inom Fallskärmsprojektet. Projektet genomfördes vid 17 psykiatriska kliniker i Sverige och patienterna erbjöds en "behovsanpassad" psykiatrisk behandling, huvudsakligen i öppen vård och uppföljning under fem år, med syfte att få en positiv inverkan på sjukdomsförloppet. READ MORE