Search for dissertations about: "FGF-2"
Showing result 11 - 15 of 39 swedish dissertations containing the word FGF-2.
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11. Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction
Abstract : Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. READ MORE
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12. The role of VEGF family in angiogenesis, tumor growth and metastasis
Abstract : Tumor growth is dependent on angiogenesis, and cells in tumor tissues produce various angiogenic factors to induce neovascularization. Among tumor-derived angiogenic factors, members of the vascular endothelial growth factor (VEGF) family are most frequently and highly expressed in various solid tumors. READ MORE
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13. Angiogenesis in childhood malignancies
Abstract : Angiogenesis is necessary for the growth and spread of solid tumors. In these studies angiogenesis was measured in childhood malignancies in general and in Wilms’ tumor in particular, and cutting needle biopsy (CNB) specimens were evaluated for diagnosis in childhood renal tumors. READ MORE
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14. Hem- and lymph-angiogenesis in cancer metastasis
Abstract : Angiogenesis, the process of sprouting new microvessels from the preexisting vasculature, is known to promote tumor growth. However, the role of tumor angiogenic vessels in facilitating metastasis remains poorly understood. READ MORE
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15. Molecular mechanisms of VEGF-mediated angiogenesis and vascular permeability
Abstract : Angiogenesis, sprouting of new capillaries from pre-existing blood vessels, is a tightly regulated multi-step process. One of the key mediators in this process is the Vascular Endothelial Growth Factor (VEGF). Many tumors express high levels of VEGF and pathological angiogenesis is considered a hallmark of malignant tumor growth. READ MORE