Search for dissertations about: "FH"

Showing result 1 - 5 of 27 swedish dissertations containing the word FH.

2. 1. Mutation Analysis and Hypercholesterolemia: Studies in FH patients and in healthy middle-aged men with high, low, or increasing cholesterol levels during a six-year follow-up (the CRISS study)

   Author : Ulf Ekström; Avdelningen för klinisk kemi och farmakologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; LDL receptor; Mutation; risk factor; FH; familial hypercholesterolemia;

   Abstract : Our aims were to characterize familial hypercholesterolemia (FH) in a Swedish FH population and to further elucidate the clinical expression and treatment response in relation to genotype. Secondly, we wanted to identify gene variants, which may have impact on cholesterol levels in apparently healthy subjects. READ MORE

4. 2. Structural and functional studies of C4b-binding protein (C4BP)

   Author : Lena Kask; Malmö Klinisk kemi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phagocytosis; apoptosis; protein S; complement control protein CCP domains; factor H fH ; Complement; C4b-binding protein C4BP ; intracellular assembly; Clinical chemistry; Klinisk kemi;

   Abstract : The subject of this thesis is complement inhibitor C4b-binding protein (C4BP), on which we have performed both structural and functional studies. Complement is part of the innate immune defence and eliminates microbes, solubilises immune complexes and is involved in the clearance of apoptotic cells. READ MORE

5. 3. Coding for multiple-access and fading channels

   Author : Leif Wilhelmsson; Institutionen för elektro- och informationsteknik; []
   Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Systems engineering; Gilbert-Elliott channel model; Imperfect interleaving; Fading; Error correcting codes; Pre-coding; Channel capacity; Direct-sequence code-division multiple-access DS-CDMA ; Frequency-hopped code-division multiple-access FH-CDMA ; computer technology; Data- och systemvetenskap; Telecommunication engineering; Telekommunikationsteknik;

   Abstract : This thesis treats some information-theoretical and coding aspects of communication over multiple-access and fading channels. It consists of a general introduction and seven papers. In code-division multiple-access (CDMA) communication, many users have access to the channel simultaneously. READ MORE

6. 4. Mechanisms of phagocytosis resistance in Streptococcus pyogenes

   Author : Heike Kotarsky; Lund Pediatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; fibrinogen; FHL-1; Factor H; M protein; Streptococcus pyogenes; phagocytosis;

   Abstract : A distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and fibrinogen that plays a key role in coagulation. READ MORE

7. 5. Familial hypercholesterolemia in Sweden : genetic and clinical studies

   Author : Peter Benedek; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Prevention of premature disease and death from cardiovascular complications of atherosclerosis is an important goal for public health, and the early identification of individuals with increased risk is an important goal of modern medicine. Familial hypercholesterolemia (FH) is one of the most common monogenic diseases (1/250 to 1/300) where strong evidence of positive health effects of intervention has been established. READ MORE