Search for dissertations about: "FLD"

Showing result 1 - 5 of 7 swedish dissertations containing the word FLD.

  2. 1. Translational genetics identifies a novel target to treat fatty liver disease

    Author : Kavitha Sasidharan; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fatty liver disease; human genetics; GWAS; PSD3; spheroids;

    Abstract : Fatty liver disease (FLD) is rapidly prevailing as the most common liver disease worldwide, with an estimated of one-quarter of the global population affected. Environmental and genetic determinants contribute to FLD susceptibility. READ MORE

  4. 2. MRI and SPECT neuroimaging in mild cognitive impairment and Alzheimer's disease

    Author : Per Julin; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : This thesis concerns measurements of regional brain volumes using Magnetic Resonance Imaging (MRI) and of regional cerebral blood flow (CBF) using Single Photon Emission Computed Tomography (SPECT) in patients investigated for suspected dementia. In the first study (I), visually rated MRI-, SPECT and EEG-pathology were compared between patients with Alzheimer's disease (AD) and patients with Frontal Lobe Dementia (FLD). READ MORE

  5. 3. Regulators of Membrane Fluidity

    Author : Kiran Busayavalasa; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRIG; membrane fluidity;

    Abstract : Caenorhabditis elegans PAQR-2 (a homolog of the mammalian AdipoR1 and AdipoR2 proteins) and IGLR-2 (homolog of the mammalian LRIG proteins) form a complex at the plasma membrane that regulates fatty acid desaturation to protect against saturated fatty acid-induced membrane rigidification. Maintenance of membrane homeostasis is fundamental for most cellular processes and, given its importance, robust regulatory mechanisms must exist that adjust lipid composition to compensate for dietary variation. READ MORE

  6. 4. Membrane Fluidity Regulation: From C. elegans to mammalian cells

    Author : Ranjan Devkota; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; PAQR-2; adiponectin receptors; IGLR-2; saturated fats; membrane fluidity; fatty acid desaturation; unsaturated fatty acid; membrane homeostasis;

    Abstract : Biological membranes are primarily an assembly of lipids and proteins. Collectively, these constituents within a phospholipid bilayer determine the physical membrane properties such as fluidity, viscosity, thickness, packing and permeability. Maintenance of membrane properties within acceptable margins, i.e. READ MORE

  7. 5. Simulation of bending and hydroforming : constitutive modeling and failure prediction

    Author : Mikael Jansson; Linköpings universitet; []
    Keywords : hydroforming; anisotropy; aluminium; finite element simulation; forming limits;

    Abstract : In recent years, the automotive industry has shown increased interest in reducing weight and improving environmental effects of cars. This has lead to an increased use of lightweight parts. READ MORE