Search for dissertations about: "FOXC2"

Showing result 1 - 5 of 7 swedish dissertations containing the word FOXC2.

  2. 1. FOXC2 : a regulator of adipocyte metabolism

    Author : Anna Cederberg; Göteborgs universitet; []
    Keywords : FOXC2; forkhead; winged helix; obesity; diabetes; adipocyte; insulin resistance;

    Abstract : Obesity, hyperlipidemia and insulin resistance are common forerunners of type 2 diabetes, a serious and increasingly prevalent disease in both the industrialised part of the world as well as in third world countries. We have identified the human transcription factor gene FOXC2 as a key regulator of adipocyte metabolism. READ MORE

  4. 2. Foxf2 and Foxc2, two transcription factors that regulate adipocyte metabolism

    Author : Rickard Westergren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; forkhead genes; insulin signaling; glucose metabolism; adipose tissue; angiogenesis; Foxc2; Foxf2; Irs1; insulin resistance; Ang-2;

    Abstract : Type 2 diabetes is the most common metabolic disorder today and has reached epidemic proportions in many countries. Diet-induced insulin resistance plays a central role in the development of type 2 diabetes. READ MORE

  5. 3. FOXC2 and CAPN10 as candidate genes for obesity, insulin resistance and type 2 diabetes

    Author : Emma A Nilsson; diabetes och endokrinologi Genomik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; Type 2 diabetes; Genetics; Obesity;

    Abstract : The worldwide prevalence of obesity and type 2 diabetes is increasing rapidly. Both disorders depend on genetic and environmental factors. The studies included in this thesis investigated the possible association of the FOXC2 and CAPN10 genes with obesity, insulin resistance, type 2 diabetes, and related phenotypes. READ MORE

  6. 4. Human iris characteristics as biomarkers for personality

    Author : Mats Larsson; Håkan Stattin; Nancy Pedersen; Richard J. Rose; Örebro universitet; []
    Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Personality; iris characteristics crypts pigment dots contraction furrows; candidate genes MITF PAX6 SIX3 LMX1B FOXC1 FOXC2 PITX2 BMP4 OLFM3 MSX1 MSX2; anterior cingulate; genetic correlations; heritability; hemispheric asymmetries; approach-related behaviors; Psychology; Psykologi; Psykologi; Psychology;

    Abstract : This dissertation explains why behavioral genetic research can be better informed by using characteristics in the human iris as biomarkers for personality, and is divided into five parts. Part I gives an introduction to the classical twin method and an overview of the findings that have led most developmental researchers to recognize that the normal variation of personality depends on a complex interplay between genetic and environmental factors. READ MORE

  7. 5. Mechanism of pathological angiogenesis in adipose tissue and tumor

    Author : Yuan Xue; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Angiogenesis is critical for both malignant diseases, such as cancer, and non-malignant diseases, such as obesity and metabolic disorders. Majority of tissues and organs are highly vascularized. The malfunctions of tissue microenvironment are always accompanied with or dependent on the alterations of vasculature. READ MORE