Search for dissertations about: "FRET biosensor"

Found 5 swedish dissertations containing the words FRET biosensor.

  1. 1. Fluorescence-based ligand assays for protein detection using affibody affinity proteins

    University dissertation from Stockholm : KTH

    Author : Björn Renberg; Amelie Eriksson Karlström; Per-Åke Nygren; Jörg Hoheisel; [2006]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Affibody molecules; biosensors; FRET; immobilisation; solid-phase synthesis; protein microarrays; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi;

    Abstract : The detection and quantification of biomolecules, and proteins in particular, are of great interest since these molecules are of fundamental importance to our well-being. Body fluids, as for instance human blood, are well suited for sampling of protein levels. READ MORE

  2. 2. Modeling Biochemical Network Involved in Striatal Dopamine Signaling

    University dissertation from KTH Royal Institute of Technology

    Author : Anu G. Nair; Jeanette Hellgren Kotaleski; Omar Gutierrez Arenas; Upinder Singh Bhalla; Jakob Kisbye Dreyer; [2018]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dopamine signaling; Striatum; Reward learning; Acetylcholine; Mass-action modeling; FRET biosensor; Adenosine; Eligibility trace; Datalogi; Computer Science;

    Abstract : In this thesis, I studied the molecular integration of reward-learning related neuromodulatory inputs by striatal medium-sized projection neurons (MSNs) using mass-action kinetic modeling.It is known that, in reward learning, an unexpected reward results in transient elevation in dopamine (peak) whereas omission of an expected reward leads to transient dopamine decrease (dip). READ MORE

  3. 3. Hydrogels of conjugated polyelectrolytes for biosensor and biochip applications

    University dissertation from Linköping : Linköpings universitet

    Author : Peter Åsberg; Karin D. Caldwell; [2005]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : This thesis describes the use of conjugated polyelectrolytes (CPEs) in biosensor devices. The method is based on non-covalent assembly of the biomolecule of interest and the CPE functioning as the reporter, in one case as a transducer, of biomolecular events. READ MORE

  4. 4. Cell cycle regulation and DNA damage response : a record of polo-like kinase 1 activity

    University dissertation from Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Author : Elvira Hukasova; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Division and cell proliferation is an essence of life. A human cell has in its core a very simple yet a very complex machinery to coordinate cell cycle activities and events. READ MORE

  5. 5. Protein Interaction Studies with Low Molecular Weight Ligands Applications for Drug Discovery, Basic Research and Diagnostic Tool Design

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Tony Christopeit; U.Helena Danielson; Danièle Altschuh; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : In this thesis, the interactions between different proteins and small ligands were characterized by surface plasmon resonance spectroscopy (SPR) and fluorescence resonance energy transfer (FRET) based assays.   For the C-reactive protein (CRP), a new type of artificial binder was identified which allows designing diagnostic assays superior to commonly used standard assays. READ MORE