Search for dissertations about: "FUNCTIONAL-RESPONSES"

Showing result 16 - 20 of 36 swedish dissertations containing the word FUNCTIONAL-RESPONSES.

  2. 16. Modulation of Receptor Signaling and Functional Selectivity in Neutrophils

    Author : Michael Gabl; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neutrophils; G-protein coupled receptors; reactive oxygen species; ligands; functional selectivity; allosteric modulation;

    Abstract : Neutrophils are important effector cells of the innate immune system and in the regulation of inflammation. Many of their functions, such as chemotactic migration, secretion of granule constituents and activation of the oxygen radical-producing NADPH-oxidase, are regulated by cell surface receptors. READ MORE

  4. 17. Sensory neurons : stem cells and development

    Author : Jens Hjerling-Leffler; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Sensory neuron; stem cells; development; boundary cap; GABA; TRPV 1; TRPA 1; TRPM8; calcium imaging; Foxs 1; SSEA-1; Schwann cells;

    Abstract : The sensory nervous system is the only means we have of communicating with the surrounding world. The neurons responsible for the sensation of pain, touch, the ability to know the position of our limbs and part of maintenance of body posture are located in the dorsal root ganglia (DRG). READ MORE

  5. 18. Evolutionary and Pharmacological Studies of NPY and QRFP Receptors

    Author : Bo Xu; Dan Larhammar; Samuel Svensson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Neuropeptide Y; genome duplication; Evolution; vertebrate; Pharmacology; Modelling; Kinetics; Bioinformatik; Bioinformatics; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot evolutionär funktionsgenomik; Biology with specialization in Evolutionary Functional Genomics; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Abstract : The neuropeptide Y (NPY) system consists of 3-4 peptides and 4-7 receptors in vertebrates. It has powerful effects on appetite regulation and is involved in many other biological processes including blood pressure regulation, bone formation and anxiety. READ MORE

  6. 19. In situ remediation of contaminated sediments using thin-layer capping : effectiveness in contaminant retention and ecological implications

    Author : Göran Samuelsson; Jonas Gunnarsson; Maria Granberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Thin layer capping; sediment remediation; activated carbon; contaminated sediment; benthic community; Systems Ecology; systemekologi;

    Abstract : Hydrophobic organic contaminants (HOCs) often reside in sediment sorbed to particles, most tightly to particles with high content of organic carbon. If persistent, such pollutants can accumulate in the sediment for many years and constitute a contamination risk for sediment-living organisms and organisms at higher trophic levels, including humans. READ MORE

  7. 20. α1-acid glycoprotein modulates the function of human neutrophils and platelets

    Author : Peter Gunnarsson; Magnus Grenegård; Henrik Thorlacius; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The acute-phase protein α1-acid glycoprotein (AGP; orosomucoid) was initially identified andcharacterised in the 1950s. The normal plasma concentration is around 0.5-1 mg/ml butduring inflammation the concentration increase several fold and the carbohydrate compositionof the protein changes. READ MORE