Search for dissertations about: "FUS"

Showing result 6 - 10 of 19 swedish dissertations containing the word FUS.

  2. 6. Functional roles of protein phase separated assemblies in cellular stress response and proteinopathies

    Author : Michelle Lindström; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; phase separation; LLPS; stress granules; Lsm7; FUS; Ccr4;

    Abstract : For a long time, pertinent biological conundrums, such as the organization and compartmentalization of the cytoplasm and nucleoplasm, perplexed the scientific community. The organization of the complex biochemistry in an accurate space and time manner could not be explained without the enclosure of a membrane. READ MORE

  4. 7. EWSR1 and FUS fusion genes in tumorigenesis

    Author : Emely Möller; Avdelningen för klinisk genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The present thesis concerns the involvement of EWSR1 and FUS fusion genes, and the chimeric proteins they encode, in tumorigenesis. In Article I, the EWSR1 promoter, which regulates the expression of EWSR1 fusion genes, was characterized and regions that were crucial for promoter activity could be identified. READ MORE

  5. 8. What is all the fus about EF-G?

    Author : Urban Johanson; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  6. 9. Liposarcomas - proliferation, senescence and the role of DDIT3

    Author : Christina Kåbjörn-Gustafsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Liposarcoma; FUS-DDIT3; TP53; senescence;

    Abstract : Lipomatous tumors comprise benign and malignant forms called lipomas and liposarcomas. Myxoid/round cell liposarcoma (MLS/RCLS) is the second most common liposarcoma and is characterized by the fusion oncogenes FUS-DDIT3 or EWSR1-DDIT3. READ MORE

  7. 10. RNA binding proteins and epigenetics in SCA7

    Author : Frida Niss; Anna-Lena Ström; Ann-Kristin Östlund-Farrants; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Abstract : Polyglutamine diseases are a group of nine disorders that includes, among others SCA7. The common denominator is an expanded glutamine tract in the respective disease protein caused by unstable replication during meiosis. READ MORE