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Showing result 1 - 5 of 405 swedish dissertations matching the above criteria.

2. 1. Interactions between platelets and complement with implications for the regulation at surfaces

   Author : Per H. Nilsson; Kristina Nilsson Ekdahl; John Lambris; Ian Nicholls; Berhane Ghebrehiwet; Linnéuniversitetet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system activation; regulation ; platelets activation; regulation ; biomaterials; biocompatibility; chondroitin sulfate-A; apyrase; C1q; C3; factor H; C4BP; ADP; Biomedical Sciences; Biomedicinsk vetenskap;

   Abstract : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. READ MORE

4. 2. Deciphering the Alk signaling pathway in Drosophila

   Author : Fredrik Hugosson; Ruth H. Palmer; Osamu Shimmi; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Drosophila; Alk; RTK; visceral mesoderm; signal transduction; growth factor; transcription factor; molekylärbiologi; Molecular Biology;

   Abstract : In Drosophila melanogaster the visceral mesoderm (VM) develops during embryogenesis in a process where myoblasts become specified to generate two distinct cell types, the founder cells (FCs) and the fusion competent myoblasts (FCMs) that consequently fuses. The cell specification is dependent on cell signaling mediated by the receptor tyrosine kinase (RTK) Anaplastic lymphoma kinase (Alk) and its ligand Jelly belly (Jeb), how this further sets up different identity programs that drive myoblasts to differentiate into FCs and FCMs is still not well understood. READ MORE

5. 3. Quantum mechanical studies of ionization and electron transfer in diatomic systems : O2 and H+ + H-

   Author : Michael Stenrup; Hans Ågren; KTH; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi;

   Abstract :   The present thesis is based upon two papers concerning the core-valence double onization of molecular oxygen and mutual neutralization of H+ and H- ions at low collision energies. The former of these processes has been studied for the first time using a magnetic bottle time-of-ight electron coincidence spectrometer in combination with ab initio electronic structure calculations. READ MORE

6. 4. Run-Up Transient Analysis for Salient Pole Wound Field Synchronous Motors : Field winding and power electronics implications for a smoother and cooler asynchronous start

   Author : Roberto Felicetti; Urban Lundin; Andreas Binder; Uppsala universitet; []
   Keywords : apparent resistance; cable modeling; current control; transmission line model; eddy currents; field winding; frequency analysis response; Fourier Transform; impedance mismatch; main inductance; overvoltage; parasitic capacitance; partial discharge; quality factor; ringing; slew rate; stray inductance; voltage gradient; winding resonance frequency; asynchronous start; run-up; torque ripple; reluctance torque; Engineering Science with specialization in Science of Electricity; Teknisk fysik med inriktning mot elektricitetslära;

   Abstract : Salient Pole Wound Field Synchronous Machines have better efficiency at full load than asynchronous machines of the same capability. Moreover, where asynchronous machines need inherently to draw a magnetizing current from the grid, Salient Pole Wound Field Synchronous Machines can work efficiently at unity power factor. READ MORE

7. 5. Anaplastic Lymphoma Kinase mutations and downstream signalling

   Author : Christina Schönherr; Ruth H Palmer; Aristidis Moustakas; Umeå universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Anaplastic Lymphoma Kinase; oncogene; RTK; neuroblastoma; crizotinib; NVP-TAE684; gain-of-function; MYCN; transcription factor; small GTPase; Rap1; C3G; PC12 cells; neurite outgrowth; molecular cell biology; molekylär cellbiologi;

   Abstract : The oncogene Anaplastic Lymphoma Kinase (ALK) is a Receptor Tyrosine Kinase (RTK) and was initially discovered as the fusion protein NPM (nucleophosmin)-ALK in a subset of Anaplastic Large Cell Lymphomas (ALCL). Since then more fusion proteins have been identified in a variety of cancers. READ MORE