Search for dissertations about: "Farmaceutisk biovetenskap"
Showing result 6 - 10 of 206 swedish dissertations containing the words Farmaceutisk biovetenskap.
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6. Discovery of Novel Fatty Acid Dioxygenases and Cytochromes P450 : Mechanisms of Oxylipin Biosynthesis in Pathogenic Fungi
Abstract : Dioxygenase-cytochrome P450 (DOX-CYP) fusion enzymes are present in diverse human and plant pathogenic fungi. They oxygenate fatty acids to lipid mediators which have regulatory functions in fungal development and toxin production. READ MORE
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7. Co-operative recombination mechanisms promoting gene clustering and lateral transfer of antibacterial drug resistance
Abstract : Transposons of the Mu superfamily are widespread and have been shown to play an important role in the dissemination of antibiotic resistance among microorganisms. One of these elements, Tn5090/Tn402 is the basal vehicle of the type 1 integrons in which mobile resistance gene cassettes are inserted to form clusters and operons. READ MORE
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8. The Role of Cyclooxygenase-2 in Models of Epilepsy and Traumatic Brain Injury : Effects of Selective Cyclooxygenase-2 Inhibitors
Abstract : Cyclooxygenase-2 (COX-2) catalyses prostaglandin synthesis from arachidonic acid during inflammation. COX-2 is expressed in the normal brain and is induced in neurological disorders. There is evidence that COX-2 is involved in secondary events leading to cell death in the brain. READ MORE
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9. Arachidonic acid metabolism in corneal epithelial cells : Identification of lipoxygenase isoforms
Abstract : The metabolism of arachidonic acid in the human cornea was investigated and compared with the metabolism in cattle and primates. All three species showed significant arachidonic acid metabolism inthe epithelium, whereas the activity in the stroma and the endothelium was low or undetectable. READ MORE
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10. The Role of the Melanocortin System in Linking Energy Homeostasis with Reward Mechanisms
Abstract : There is evidence of a link between peripheral signals of energy homeostasis and reward mechanisms. A hypothesis was formulated that the melanocortin (MC) system is part of this link. The hypothesis was tested by a series of receptor expression and neurochemical studies in rats. READ MORE