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Showing result 1 - 5 of 520 swedish dissertations matching the above criteria.

2. 1. Spontaneous reporting of adverse drug reactions : Possibilities and limitations

   Author : Martin Bäckström; Tom Mjörndal; Rune Dahlqvist; Folke Sjökvist; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; adverse drug reactions; spontaneous reporting; metamizole; general practitioners; hospital physicians; under-reporting; economical inducement; nurses.; Farmakologi; Pharmacological research; Farmakologisk forskning; Clinical Pharmacology; klinisk farmakologi;

   Abstract : Adverse drug reactions (ADRs) constitute a major problem in society and in drug therapy. They are a common cause of short-term hospitalization, prolonged hospitalization and death. Spontaneous reporting of ADRs remains one the most effective methods for detecting new and serious drug reactions. READ MORE

4. 2. Transcription Factor AP-2 in Relation to Serotonergic Functions in the Central Nervous System

   Author : Mattias Damberg; Elias Eriksson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; CNS; serotonin; transcription factors; AP-2; personality; antidepressants; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

   Abstract : Eukaryotic gene transcription plays a regulatory role in mammalian developmental processes. It has been shown that transcriptional control is an important mechanism for specification of neurotransmitter phenotypes. READ MORE

5. 3. Fatty acid amide hydrolase - A target for anti-inflammatory therapies?

   Author : Sandra Holt; Christopher J Fowler; Anders Bucht; Gunnar Tiger; Ruth A Ross; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; FAAH; anandamide; endocannabinoid; pH; inflammation; NSAID; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

   Abstract : Anti-inflammatory drugs are a widely used class of therapeutic agents, but the use of non-steroidal anti-inflammatory drugs (NSAID) is hampered by their gastrointestinal side-effects. Recent reports that cyclooxygenase-2 inhibitors may cause cardiovascular events underline the importance of identifying new therapeutic strategies for the treatment of inflammation. READ MORE

6. 4. Pharmacology of Palmitoylethanolamide and Related Compounds

   Author : Kent-Olov Jonsson; Christopher J Fowler; Gunnar Tiger; Andrew SC Rice; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; anandamide; cannabinoid; FAAH; palmitoylethanolamide; palmitoylisopropylamide; inflammation; mast cells; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

   Abstract : Anandamide (AEA) is an endogenous fatty acid which activates the same cannabinoid receptors as ∆9-tetrahydrocannabinol, the psychoactive substance in marijuana. In vivo, anandamide exerts a number of actions including effects upon pain and inflammation. READ MORE

7. 5. Semicarbazide-sensitive amine oxidase and vascular complications in diabetes mellitus : Biochemical and molecular aspects

   Author : Jenny Nordquist; Keith F. Tipton; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; diabetes; SSAO; VAP-1; retinopathy; methylamine; aminoacetone; hydralazine; Farmakologi; Pharmacological research; Farmakologisk forskning; medicinsk farmakologi; Medical Pharmacology;

   Abstract : Plasma activity of the enzyme semicarbazide-sensitive amine oxidase (SSAO; EC.1.4.3. READ MORE