Search for dissertations about: "Fas-FasL"
Showing result 1 - 5 of 10 swedish dissertations containing the word Fas-FasL.
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1. Regulation of T-cell proliferation and B-CLL apoptosis by CD6 and FAS/FASL
Abstract : T-cell activation involves the interaction between the T-cell receptor (TCR) and the peptide/MHC complex presented on an antigen-presenting cell. However, this is not sufficient for the full development of T cell responses and co-stimulatory signals from accessory molecules are required. READ MORE
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2. Dysregulation of receptor induced apoptosis during human leishmaniasis : a possible mechanism of skin ulceration
Abstract : Leishmaniasis is endemic in 88 countries and 12 million people per year have been estimated to be at risk of infection. The causative agent, the protozoan Leishmania, is spread by sand-flies and infects macrophages in the mammalian host. Leishmaniasis in humans form a spectrum of clinical presentations. In cutaneous leishmaniasis (CL) caused by L. READ MORE
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3. Immune activation during HIV-1 infection : implication for B cell dysfunctions and therapy monitoring
Abstract : Aberrant activation of cells of the immune system plays a major role in the pathogenesis of HIV infection. The major aims of the thesis were: (a) to measure the effects of current antiretroviral therapy on immune activation through the analysis of soluble activation markers; (b) to evaluate the extent of T and B cell immune activation in relation to immunological and virological parameters; (c) to analyse the T-B cell molecular pathway leading to hyperactivation of B cells and loss of B cell function. READ MORE
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4. The HER2/neu oncoprotein and dendritic cells in immunity against tumors
Abstract : It is now well established that small peptide epitopes bound to the major histocompatibility complex (MHC), derived from processed proteins synthesized by the tumor cells, can be recognized as antigens by cytotoxic T lymphocytes (CTLs). A number of tumor antigens recognized by CTLs on human melanomas have been defined, but less is known about antigens from other tumor types. READ MORE
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5. Extrathymic T cell receptor gene rearrangement in human alimentary tract
Abstract : T lymphocytes regulate the initiation, duration, and magnitude of adaptive immune responses and function as effector cells in cell mediated immunity. To become immunologically competent they must generate functional antigen receptors. This process takes place in the thymus and requires somatic recombination of T cell receptor (TCR) genes. READ MORE
