Search for dissertations about: "FcγRI"

Showing result 1 - 5 of 12 swedish dissertations containing the word FcγRI.

  1. 1. CD64 (FcγRI) Expression on Neutrophil Granulocytes A Diagnostic Marker of Acute Bacterial Infections

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Gustav Fjaertoft; Uppsala universitet.; [2005]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; CD64; FcγRI; Neutrophil; Infection; Newborn; Neonate; Pediatrik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Paediatric medicine; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Pediatrisk medicin;

    Abstract : Background. Newborn infants, especially preterm infants, have an increased susceptibility to serious and overwhelming bacterial as well as fungal infections. Symptoms of septicaemia in especially the very preterm neonates are vague and unspecific. READ MORE

  2. 2. Signal Transduction in Malignant Cells – Transformation, Activation and Differentiation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Karin Kårehed; Uppsala universitet.; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Molecular medicine; transformation; PDGF; PI3K; Rho-GTPase; U-937; FcγRI; macrophage; Stat1; PKR; NFκB; ATRA; differentiation; Molekylärmedicin; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Molecular medicine genetics and pathology ; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Molekylär medicin genetik och patologi ; Pathology; Patologi;

    Abstract : All aspects of cell life are regulated by signal transduction mechanisms. This thesis describes the regulatory roles of a few key signal transduction molecules involved in three major biological responses. READ MORE

  3. 3. Feedback Enhancement of Antibody Responses via Complement and Fc Receptors

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Jörgen Dahlström; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mouse; transgenic knockout; immune regulation; B lymphocytes; Fc receptors; complement; IgG; IgM; IgE; Fc-gamma-RI; Fc-gamma-RII; Fc-gamma-RIII; CR1; CR2; CD21; CD35; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Pathology; patologi;

    Abstract : IgG, IgM and IgE in complex with antigen have the capacity to regulate specific immune responses. In this investigation, the role of Fc receptors for IgG (FcγRI, FcγRII and FcγRIII) and complement receptors 1 and 2 (CR1/2) for antibody-mediated enhancement of antibody responses are investigated. READ MORE

  4. 4. Fc receptors and feedback regulation by antibodies

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Mikael Karlsson; Uppsala universitet.; [1999]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Mouse; B lymphocytes; Fc; receptors; IgG; IgE; FcgRI; FcgRII; FcgRIII; Fc e RI; CD23; Rh prophylaxis; Haemolytic disease of the newborn; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik; Pathology; patologi;

    Abstract : The purpose of this investigation was to determine the role of Fc receptors for IgG (FcγRI, FcγRIIB, FcγRIII and FcRn) in immunoregulation. IgG is known to enhance the response to soluble antigens such as bovine serum albumin whereas the response to particulate antigens is suppressed. READ MORE

  5. 5. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Sofia Magnusson; Uppsala universitet.; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fc gamma receptors; rheumatoid arthritis; antibodies; mast cells; mast cell; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; Immunologi; Immunology;

    Abstract : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. READ MORE