Search for dissertations about: "Fibroblast Growth Factor 4"

Showing result 11 - 15 of 52 swedish dissertations containing the words Fibroblast Growth Factor 4.

  2. 11. Heparan Sulfate Regulation of Fibroblast Growth Factor (FGF) Receptor-1 Signal Transduction

    Author : Lars Lundin; Lena Claesson-Welsh; Marco Presta; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; FGF; FGFR; dimerisation; signal transduction; heparan sulfate; proteoglycan; heparin; VEGF; embryonal stem cell; endothelial cell; differentiation; Patologi; Pathology; Patologi;

    Abstract : Fibroblast growth factors (FGFs) constitute a family (currently FGF-1 to FGF-23) of polypeptides that are essential in embryonal development and adult physiology, in animals from nematodes to humans. FGFs bind to four receptor tyrosine kinases, denoted FGFR-1 to FGFR-4. READ MORE

  4. 12. Aspects of Fibroblast Growth Factor 23 in Mild to Moderate Renal Dysfunction

    Author : Per-Anton Westerberg; Torbjörn Linde; Östen Ljunggren; Björn Wikström; Marcus Ketteler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; phosphate; mineral metabolism; elderly; mortality; Medicin; Medicine;

    Abstract : Disturbances in mineral metabolism contribute to vascular calcification and mortality risk in chronic kidney disease (CKD). Serum levels of fibroblast growth factor (FGF)23, a bone derived, phosphaturic peptide, are associated with cardiovascular mortality in CKD. READ MORE

  5. 13. The role of fibroblast growth factor-23 in chronic kidney disease-mineral and bone disorder

    Author : Majd A. I. Mirza; Tobias Larsson; Tilman Drüeke; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; FGF-23; CKD; CKD-MBD; cardiovascular disease; vascular function; atherosclerosis; hypertrophy; LVMI; LVH; fractures; bone; fat mass; obesity; apolipoproteins; cholesterol; lipids; Kidney diseases; Njursjukdomar; Cardiovascular medicine; Kardiovaskulär medicin; Medicinsk vetenskap; Medical Science;

    Abstract : Fibroblast growth factor-23 (FGF23) was initially identified as the causative factor of autosomal dominant hypophosphatemic rickets. Further studies confirmed that FGF23 is predominantly expressed in the osteocytes and osteoblasts of bone and that circulating FGF23 acts on the kidney to inhibit renal phosphate reabsorption and 1,25(OH)2D3 hydroxylation. READ MORE

  6. 14. In vitro wound healing characteristics of amelogenins

    Author : Sofia Almqvist; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amelogenins; extracellular matrix; cell culture; macrophage; fibroblast; endothelial cell; integrin; cytokine; inflammation; wound healing tissue repair;

    Abstract : Wound healing involves the co-ordinated actions of several cell types, soluble cell mediators and extracellular matrix (ECM). This research project intended to investigate the role of certain ECM proteins in different processes during tissue repair by studying the interaction between dermal cells and ECM. READ MORE

  7. 15. On growth factors and titanium implant integration in bone

    Author : Victoria Franke Stenport; Göteborgs universitet; []
    Keywords : growth factors; signal peptides; titanium implants; osseointegration; in vivo studies;

    Abstract : PurposeThe purpose of the present thesis was to investigate the bone tissue response around titanium implants with one growth factor stimulating hormone and a few different growth factor substances.Material and methodsIn four studies (study I to IV) a rabbit model were used and the growth factors i.e. READ MORE