Search for dissertations about: "Fibroblasts"

Showing result 16 - 20 of 404 swedish dissertations containing the word Fibroblasts.

  2. 16. From a Road Less Travelled to a Worn Path: Three-Dimensional Tumour Models for Cancer Research and Therapeutics

    Author : Atena Malakpour Permlid; NanoLund: Centre for Nanoscience; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 3D tumour models; scaffold-based cultures; cancer cells; electrospun scaffolds; extracellular matrix; tumour microenvironment; high-throughput screening; animal-free; donor herd horse serum; fibroblasts;

    Abstract : Cancer is the second leading cause of death among both men and women worldwide. During therecent years, three-dimensional (3D) tumour models have gained increasing interest as a pre-clinicalplatform for screening of compounds for potential use in cancer therapy. READ MORE

  4. 17. Identification and clinical evaluation of senescence-associated markers to distinguish melanocytic nevi from melanomas

    Author : Kyriakos Orfanidis; Ingrid Synnerstad; Jakob Wikström; John Paoli; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; senescence; nevi; melanoma; melanocytes; fibroblasts; ultraviolet UV radiation;

    Abstract : Melanoma is a form of cancer that develops in melanocytes. While it represents only 5% of skin malignancies, it is the most aggressive and lethal. Benign proliferation of these cells form the melanocytic nevi. The definitive diagnosis of melanocytic nevi or melanoma lesions is histopathologic. READ MORE

  5. 18. Integration of functional genomics and data mining methodologies in the study of bipolar disorder and schizophrenia

    Author : Marianthi Logotheti; Nikolaos Venizelos; Fragiskos Kolisis; Nikos Stefanis; Örebro universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar Disorder; Schizophrenia; Fibroblasts; DNA Microarrays; Machine Learning; Functional Analysis; Gene Expression; Transcriptomics;

    Abstract : Bipolar disorder and schizophrenia are two severe psychiatric disorders characterized by a complex genetic basis, coupled to the influence of environmental factors. In this thesis, functional genomic analysis tools were used for the study of the underlying pathophysiology of these disorders, focusing on gene expression and function on a global scale with the application of high-throughput methods. READ MORE

  6. 19. Nanostructuring of polymeric biomaterial surfaces

    Author : Hossein Agheli; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; polymers; electrostatic self assembly; nanofabrication; morphology; colloidal lithography; fibroblasts; adhesion;

    Abstract : .... READ MORE

  7. 20. Mast cells and its crosstalk with mesenchymal cells in chronic lung diseases

    Author : Mariam Bagher; allergologi och palliativ medicin Lungmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mast cells; Fibroblasts; IPF; COPD; Extracellular matrix; Remodelling; Inflammation; Tryptase; Chymase; Protease-activated receptor 2; Migration;

    Abstract : .... READ MORE