Search for dissertations about: "Fide"

Showing result 16 - 20 of 41 swedish dissertations containing the word Fide.

  2. 16. Programming Blood Cell Fates. Insights from Direct Lineage Conversion and Development

    Author : Sandra Capellera Garcia; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematopoietic development; Erythropoiesis; Megakaryopoiesis; Direct Lineage Conversion;

    Abstract : Red blood cells (RBC) and platelets constitute the non-immune branch of the hematopoietic system and are responsible for the vital functions of transporting oxygen to the tissues and clotting blood vessel injuries, respectively. These cells are produced during embryonic development and throughout life through a process called hematopoiesis which is tightly regulated by extrinsic and intrinsic factors. READ MORE

  4. 17. The role of Lmx1a and Lmx1b in regulating mesencephalon development and dopamine neuron specification

    Author : Qiaolin Deng; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : One of the most challenging questions in developmental biology is how neurons are specified, acquire their distinct characteristics and find their correct innervations to form functional circuits. The development of different subsets of neurons involves the expression of a program intrinsic to each cell type and the response to extrinsic environmental influences represented by soluble factors. READ MORE

  5. 18. Specification of unique neuronal sub-types by integration of positional and temporal cues

    Author : Daniel Karlsson; Stefan Thor; Mattias Alenius; Jeremy S. Dasen; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The nervous system contains vast numbers of neuronal sub-types, generated at specific time points, in the proper location, and in proper numbers. One of the fundamental issues in neurobiology is to understand the molecular genetic mechanisms that underlie the generation of this daunting neuronal diversity. READ MORE

  6. 19. Protein Quality Control at the Inner Nuclear Membrane – The Asi complex in Saccharomyces cerevisiae

    Author : Marina Pantazopoulou; Per Ljungdahl; Jaspersen Sue; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; nuclear envelope; nuclear quality control NQC ; ubiquitin; proteasome; inner nuclear membrane-associated degradation INMAD ; Cell Biology; cellbiologi;

    Abstract : The nuclear envelope is a barrier comprised of outer and inner membranes that separate the cytoplasm from the nucleoplasm. The outer (ONM) and inner (INM) membranes have different physical characteristics and protein compositions. READ MORE

  7. 20. Developmental insights and biomedical potential of human embryonic stem cells : modelling trophoblast differentiation and establishing novel cell therapies for age-related macular degeneration

    Author : Álvaro Plaza Reyes; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Understanding the molecular pathways responsible for lineage segregation in the preimplantation human embryo is critical in order to fully elucidate the mechanisms involved in pluripotency and differentiation of embryonic stem cells. A significant increase in our comprehension of such processes will lead to an improvement in the quality and efficiency of these cells for applications requiring stem cell maintenance and differentiation, such as regenerative medicine. READ MORE