Search for dissertations about: "Finland Kuopio University of Kuopio Department of Anatomy"

Found 2 swedish dissertations containing the words Finland Kuopio University of Kuopio Department of Anatomy.

  1. 1. Influences of in vivo and in vitro loading on the proteoglycan synthesis of articular cartilage chondrocytes

    Author : Mikko Lammi; Markku Tammi; Jukka Finne; Tim Hardingham; Finland Kuopio University of Kuopio Department of Anatomy; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Articular cartilage; proteoglycans; loading; stress; hydrostatic pressure; biokemi; Biochemistry; cell research; cellforskning; molekylärbiologi; Molecular Biology; ortopedi; Orthopaedics;

    Abstract : In this study, the biosynthesis of proteoglycans (PGs) was examined in articular cartilage of canine hip joint after long-distance running experiment and in bovine chondrocyte cultures during in vitro loading with hydrostatic pressure. In addition, new assays were developed for more sensitive quantitation of glycosaminoglycans (GAGs) and PGs. READ MORE

  2. 2. Articular cartilage proteoglycan biosynthesis and sulfation

    Author : Chengjuan Qu; Mikko Lammi; Heikki Helminen; Juha Töyräs; Anna-Marja Säämänen; Finland Kuopio University of Kuopio Anatomy Department of Biomedicine; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cartilage; Chondrocytes metabolism; Chondroitin sulfates; Glycosaminoglycans; Osteoarthritis; Proteoglycans; Glucosamine; Sulfation; Biochemistry; biokemi; cellforskning; cell research; Orthopaedics; ortopedi;

    Abstract : Glucosamine (GlcN) and glucosamine sulfate (GS) have been used to treat the patients with osteoarthritis(OA) as a disease-modifying agent. Previousin vitro studies have focused on the effects of GlcN or GSon cartilage metabolism, whereas in vivo studies have investigated their potential for the treatment of OA. READ MORE