Search for dissertations about: "Finn Hallböök"

Showing result 16 - 19 of 19 swedish dissertations containing the words Finn Hallböök.

  2. 16. Characterization of Retinal Progenitor Cells : Focus on Proliferation and the GABAA Receptor System

    Author : Henrik Ring; Finn Hallböök; Per Söderberg; Andras Simon; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regeneration; Proliferation; Neurotransmitters; Müller cells; Differentiation; Retinal repair; Neurogenesis; Medical Science; Medicinsk vetenskap;

    Abstract : One strategy to repair an injured or degenerated retina is to stimulate the replacement of damaged or dead neurons with cells derived from endogenous stem- or progenitor cells. A successful strategy requires knowledge about how the proliferation and differentiation of the endogenous cells are regulated. READ MORE

  4. 17. The Heterogenic Final Cell Cycle of Retinal Horizontal Cells

    Author : Shahrzad Shirazi Fard; Finn Hallböök; Ulla Pirvola; Uppsala universitet; []
    Keywords : Apoptosis; Checkpoint; DNA damage; Differentiation; Heteroploid; Endoreplication; Proliferation; Tumor; Neuroscience; Neurovetenskap;

    Abstract : The cell cycle is a highly complex process that is under the control of several pathways.  Failure to regulate and/or complete the cell cycle often leads to cell cycle arrest, which may be followed by programmed cell death (apoptosis). One cell type that has a variety of unique cell cycle properties is the horizontal cell of the chicken retina. READ MORE

  5. 18. Caspase-3 in lens epithelium

    Author : Nooshin Talebizadeh; Per Söderberg; Finn Hallböök; Konstantin Galichanin; Michael Wormstone; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ultraviolet radiation; caspase-3; lens; cataract; apoptosis; Immunohistochemistry; spatial distribution; time evolution; modelling; automatic analysis; cell counting; image analysis.; Ophtalmology; Oftalmiatrik;

    Abstract : Purpose: To model the time evolution of active caspase-3 protein expression in a healthy lens, and in a lens exposed to UVR-300 nm (UVR-B). To develop an automated method to classify the fluorescent signal of biomarkers in the lens epithelial cells.Methods: Six-week old Sprague-Dawley rats were used. READ MORE

  6. 19. Role of MYCN in retinoblastoma : From carcinogenesis to tumor progression

    Author : Hanzhao Zhang; Finn Hallböök; Johan Holmberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MYCN; retinoblastoma; RNA sequencing; cancer; avian; E2F; carcinogenesis; Developmental Neurosciences; Medicinsk utvecklings- och neurobiologi;

    Abstract : Retinoblastoma, a pediatric malignancy of the retina, is primarily driven by the bi-allelic inactivation of the RB1gene. However, a subset of cases are characterized by proficient RB1 functions but with MYCN copy number mutations, suggesting an alternative oncogenic mechanism in the absence of RB1 mutations. READ MORE