Search for dissertations about: "Flinders sensitive line"

Showing result 1 - 5 of 10 swedish dissertations containing the words Flinders sensitive line.

2. 1. On Neuroimmunology and Brain Function: Experimental and Clinical Studies

   Author : Nina Strenn; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immune system; mental disorders; polymorphisms; depression; autism; bipolar disorder; SSRI; S100B; 5-HTR2A; Flinders sensitive line;

   Abstract : The immune system has been implicated in the mechanisms underlying many psychiatric disorders. Immune mediators are expressed in the central nervous system (CNS) not only in response to harmful stimuli, but also in a constitutive manner, and serve as important plasticity factors during development. READ MORE

4. 2. On the importance of inflammation for personality traits and psychiatric morbidity

   Author : Petra Suchankova; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammation; C-reactive protein; complement factor H; S100B; receptor for advanced glycation end products; polymorphism; gene expression; personality traits; suicidal behaviour; schizophrenia; depression; Flinders sensitive line;

   Abstract : Background: Pro-inflammatory mediators have been implicated in processes that could be both beneficial and toxic to cells in the brain. On the one hand balanced levels of these mediators favour e.g. READ MORE

5. 3. On antidepressant effects of running and SSRI : focus on hippocampus and striatal dopamine pathways

   Author : Astrid Bjørnebekk; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Depression; exercise; neuropeptides; cell proliferation; neurogenesis; NPY; BDNF; Flinders Sensitive Line;

   Abstract : Considering the heterogeneous character of depression, it seems likely that many brain regions are involved mediating the diverse symptoms of depression. For example, the mesolimbic DA system has a central function for motivational behaviors and pleasure seeking, and it is possible that malfunctioning of brain reward systems could be an underlying mechanism of the anhedonia experienced in depressive illness. READ MORE

6. 4. Imbalanced kynurenine pathway in schizophrenia and depression : immunological and genetic aspects

   Author : Xicong Liu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Kynurenic acid (KYNA), an end metabolite of the kynurenine pathway along tryptophan degradation, has gained increasing interest in the pathophysiology of psychiatric disorders. Elevated levels of KYNA have been found in the cerebrospinal fluid (CSF) and in the postmortem brain of patients with schizophrenia and bipolar disorder with psychotic symptoms. READ MORE

7. 5. Antidepressive and antipsychotic treatments : effects on nerve growth factor and brain-derived neurotrophic factor in rat brain

   Author : Francesco Angelucci; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Recently it has been reported that depression and schizophrenia, the two major psychiatric disorders, are characterized by loss of neurons in specific brain regions. Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are proteins involved in neuronal survival and plasticity of dopaminergic, cholinergic and serotonergic neurons in the central nervous system (CNS). READ MORE