Search for dissertations about: "Flumazenil"

Showing result 1 - 5 of 10 swedish dissertations containing the word Flumazenil.

2. 1. 11C Molecular Imaging in Focal Epilepsy

   Author : Torsten Danfors; Eva Kumlien; Jens Sörensen; Elisabeth Ronne-Engström; Juha Rinne; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; positron emission tomography; methionine; NK1; substance p; flumazenil; deprenyl; pk11195; phosphoimager; autoradiography; TBI; traumatic brain injury; iron chloride; ferrous chloride; Neurology; Neurologi; Radiology; Radiologi;

   Abstract : Epilepsy is a common neurological disease affecting 6 million people in Europe. Early prevention and accurate diagnosis and treatment are of importance to obtain seizure freedom. In this thesis new applications of carbon-11-labelled tracers in PET and autoradiographic studies were explored in focal epilepsy. READ MORE

4. 2. Taste Hedonics and the Intake of Alcohol and Food

   Author : Anna Söderpalm; Göteborgs universitet; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Alcohol drinking; Adrenalectomy; Corticosterone; Cyanoketone; Food intake; Food restriction; GABA; Metyrapone; Taste reactivity; Benzodiazepine; Chlordiazepoxide; Cis Z -flupentixol; Diazepam; Flumazenil; Microinjections; Midazolam; Nucleus of the Solitary tract; Palatability; Parabrachial nucleus; Peduculopontine Tegmental Nucleus; Reward; 4th ventricle.;

   Abstract : This thesis includes four papers based on animal experimental work. They analyze the way in which activation of a specific motivational state - hunger- modulates the rewarding actions of alcohol and taste palatability. READ MORE

5. 3. Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments

   Author : Lars Saxon; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Abuse and dependency of alcohol or drugs is a major problem today, with severe implications for society as well as for the individual. Treatment is often characterised by hard work and the road to recovery is (among other problems) paved with acute and protracted withdrawal symptoms as well as relapse. READ MORE

6. 4. Development of in vitro and ex vivo positron-emitting tracer techniques and their application to neurotrauma

   Author : Sven Sihver; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Short-lived radionuclides; in vitro receptor binding; in vitro and ex vivo autoradiography; positron emission tomography; benzodiazepine; muscarinic acetylcholine; and NMDA receptors in CNS; experimental neurotrauma; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

   Abstract : The use of positron-emitting tracers has been extended beyond tomographic facilities in the last few years, giving rise to a general positron-emitting tracing technique. The methodological part of the present thesis involved the evaluation of the performance of storage phosphor (SP) plates, with tracers labeled with high-energy, short-lived, positron-emitting radionuclides, using homogenized tissue specimens and autoradiography with frozen brain sections. READ MORE

7. 5. Liquid Chromatography – Mass Spectrometry Analysis of Short-lived Tracers in Biological Matrices : Exploration of Radiotracer Chemistry as an Analytical Tool

   Author : Martin Lavén; Karin Markides; Bengt Långström; Rolf Ekman; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; liquid chromatography - mass spectrometry; radiotracer chemistry; positron emission tomography; biological samples; radionuclide imaging; Analytisk kemi; Analytical chemistry; Analytisk kemi;

   Abstract : Liquid chromatography – mass spectrometry (LC-MS) methods were developed for the analysis of positron emission tomography (PET) radiotracers in biological matrices. Additionally, radiotracer chemistry was explored as an analytical tool for supporting LC-MS method development and imaging molecular interactions in miniaturised chemical analysis systems. READ MORE