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Showing result 1 - 5 of 59 swedish dissertations matching the above criteria.
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1. Defining the role of CD47 and SIRPα in murine B cell homeostasis
Abstract : B cell development is a highly organized process, which commences in the fetal liver during embryogenesis and in the bone marrow (BM) after birth. Surface IgM+ immature B cells emigrate from the BM via the blood stream to the spleen and finally differentiate into conventional mature follicular B (FoB) cells and marginal zone (MZ) B cells. READ MORE
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2. Aggressive B-cell Lymphomas : Studies of Treatment, FDG-PET Evaluation and Prognostic Factors
Abstract : To improve outcome in young, high-risk lymphoma patients, treatment was intensified, adding etoposide and rituximab to standard CHOP treatment. Granulocyte-colony stimulating factor (G-CSF) enabled treatment bi-weekly. Results were promising: overall (OS) and event-free survival (EFS) 79% and 60% respectively, median follow up 27 months. READ MORE
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3. Molecular genetics of B- and T-lymphocyte development
Abstract : Lymphocytes are essential for the generation of specific immunity. Development of B cells in the bone marrow and T cells in the thymus have several analogous features, and are tightly regulated processes. Even though there is an increasing amount of information concerning lymphopoiesis, a lot of questions remain. READ MORE
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4. Follicular and Diffuse Large B-Cell Lymphoma - Studies of Primary Treatment and Prognostic Factors
Abstract : .... READ MORE
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5. Modulation of B cell access to antigen by passively administered antibodies : an explanation for antibody feedback regulation?
Abstract : Antibody responses can be up- or down-regulated by passive administration of specific antibody together with antigen. Depending on the structure of the antigen and the antibody isotype, responses can be completely suppressed or enhanced up to a 1000-fold of what is seen in animals immunized with antigen alone. READ MORE