Search for dissertations about: "Forensic mtDNA"
Showing result 1 - 5 of 9 swedish dissertations containing the words Forensic mtDNA.
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1. Sensitive Forensic DNA Analysis : Application of Pyrosequencing and Real-time PCR Quantification
Abstract : The field of forensic genetics is growing fast and the development and optimisation of more sensitive, faster and more discriminating forensic DNA analysis methods is highly important. In this thesis, an evaluation of the use of novel DNA technologies and the development of specific applications for use in forensic casework investigations are presented. READ MORE
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2. Mitochondrial Genome Analysis Using Next Generation Sequencing for Forensic Applications
Abstract : Mitochondrial DNA (mtDNA) analysis plays a specialized role in forensic applications, overcoming certain limitations of autosomal DNA markers. The high copy number and uniparental inheritance pattern of mtDNA are advantageous in cases involving shed hairs and aged skeletal elements, especially decades-old missing persons cases. READ MORE
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3. Evaluation of New Technologies for Forensic DNA Analysis
Abstract : DNA samples from crime scenes or mass disasters are often limited and degraded which limits the possibility of successful traditional STR analysis. Moreover, there is a need to decrease the turnaround time in criminal investigations. READ MORE
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4. Analysis of domestic dog mitochondrial DNA sequence variation for forensic investigations
Abstract : The first method for DNA analysis in forensics was presented in 1985. Since then, the introduction of the polymerase chain reaction (PCR) has rendered possible the analysis of small amounts of DNA and automated sequencing and fragment analysis techniques have facilitated the analyses. READ MORE
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5. Mitochondrial DNA in Sensitive Forensic Analysis
Abstract : Genetic profiling is commonly performed on the autosomes using multiple DNA markers. Although routine forensic DNA analysis is robust and based on reliable technologies, samples with degraded or limited amounts of DNA often fail. In these cases, the analysis of mitochondrial DNA (mtDNA) can be very valuable due to the high copy number per cell. READ MORE